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Autoimmune Involvement in Motor Neurone Disease

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Amyotrophic Lateral Sclerosis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 209))

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Abstract

The possibility of an autoimmune pathogenesis in motor neurone disease (MND) has been debated for many years with little consensus. However, recent evidence from different sources has served to redirect attention towards such an involvement. Thus, early findings of a serum-borne neurotoxic factor in MND patients[l] have been confirmed by Roisen et al.[2], while Gurney and his colleagues[3,4] have reported the presence in MND sera of autoantibodies to a muscle-derived growth factor for spinal neurones.

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References

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© 1987 Plenum Press, New York

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Aspin, J., Harrison, R., Jehanli, A., Lunt, G.G. (1987). Autoimmune Involvement in Motor Neurone Disease. In: Cosi, V., Kato, A.C., Parlette, W., Pinelli, P., Poloni, M. (eds) Amyotrophic Lateral Sclerosis. Advances in Experimental Medicine and Biology, vol 209. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5302-7_11

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  • DOI: https://doi.org/10.1007/978-1-4684-5302-7_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5304-1

  • Online ISBN: 978-1-4684-5302-7

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