Abstract
By using statistical structure-activity relationship (SAR) models of toxicological endpoints, it is possible to estimate the expected toxicity from structural and physical characteristics of untested chemicals. Thus, these models can be used for setting testing and developmental priorities, obtaining additional information on given compounds, and, to a lesser degree, determining what substructural factors are most involved in a particular toxicological effect.
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© 1987 Plenum Press, New York
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Enslein, K. (1987). Computer-Assisted Prediction of Toxicity. In: Tardiff, R.G., Rodricks, J.V. (eds) Toxic Substances and Human Risk. Life Science Monographs. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-5290-7_14
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DOI: https://doi.org/10.1007/978-1-4684-5290-7_14
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