Abstract
It is the premise of this chapter that there is a biological basis upon which toxicologists may be able to extrapolate from animals to humans. Its foundation lies in evolutionary theory, with the phylogenetic continuity of animal species.
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References
Agar, N. S., M. Gruca, and J. D. Harley. 1974. Studies on glucose-6-phosphate dehydrogenase, glutathione reductase, and regeneration of reduced glutathione in the red blood cells of various mammalian species. Aust. J. Exp. Biol. Med. Sci. 52:607–614.
Amma, E. L., G. D. Sproul, W. Wong, and T. H. J. Heisman. 1974. Mechanism of sickling in deer erythrocytes. Ann. N. Y. Acad. Sci. 241:605–613.
Ball, S., C. M. Hawkey, J. M. Hime, I. F. Keymer, and M. R. Brambell. 1976. Red cell sickling in genets. Comp. Biochem. Physiol. A 54:49–54.
Bannerman ,R. M., J. A. Edwards, and M. Kreimer-Birnbaum. 1974. Investigation of potential models of thalassemia. Ann. N. Y. Acad. Sci. 232:306–322.
Boxenbaum, H. 1980. Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin. J. Pharmacokin. Biopharm. 8:165–176.
Calabrese, E. J. 1983. Principles of Animal Extrapolation. Wiley, New York.
Castro, O., J. Orlin, M. W. Rosen, and S. C. Finch. 1973. Survival of human sickle-cell erythrocytes in heterologous species: Response variations in oxygen tension. Proc. Natl. Acad. Sci. USA 70:2356–2359.
Dickes, S. E. 1970. Pp. 16’30 in Mechanisms of Urine Concentration and Dilution in Mammals. Edward Arnold, London.
Feinstein, R. N., J. Braun, and J. B. Howard. 1968. Nature of the heterozygote blood catalase in a hypocatalasemic mouse mutant. Biochem. Genet. 1:277–285.
Freireich, E. J., E. A. Gehan, D. P. Rall, L. H. Schmidt, and H. E. Skipper. 1966. Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey and man. Cancer Chemother. Rep. 50:219–244.
Goldsmith, M. A., M. Slavik, and S. K. Carter. 1975. Quantitative prediction of drug toxicity in humans from toxicology in small and large animals. Cancer Res. 35:1354–1364.
Krasovskii, G. N. 1976. Extrapolation of experimental data from animals to man. Environ. Health Perspect. 13:51–58.
Maral, J., K. Puget, and A. M. Michelson. 1977. Comparative study of superoxide dismutase, catalase, and glutathione peroxidase levels in erythrocytes of different animals. Biochem. Biophys. Res. Commun. 77:1525–1535.
Maronpot, R. R. 1972. Erythrocyte glucose-6-phosphate dehydrogenase and glutathione deficiency in sheep. Can. J. Comp. Med. 36:55–60.
Paniker, N. V., and G. Y. Iyer. 1965. Erythrocyte catalase and detoxication of hydrogen peroxide. Can. J. Biochem. 43:1029–1039.
Pinkel, D. 1958. The use of body surface area as a criterion of drug dosage in cancer chemotherapy. Cancer Res. 18:853–856.
Rees Evans, E. T. 1968. Sickling phenomenon in sheep. Nature 217:74–75.
Sladic-Simic, D., P. N. Martinovich, N. Zivkovic, M. Kahn, and H. Ranney. 1969. A thalassemia-like disorder in Belgrade laboratory rats. Ann. N. Y. Acad. Sci. 165:93–99.
Weiss, M, W. Sziegoleit, and W. Förster. 1977. Dependence of pharmacokinetic parameters on the body weight. Int. J. Clin. Pharmacol. Biopharm. 15:572–575.
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© 1987 Plenum Press, New York
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Calabrese, E.J. (1987). Extrapolation from Animal Data. In: Tardiff, R.G., Rodricks, J.V. (eds) Toxic Substances and Human Risk. Life Science Monographs. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-5290-7_11
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DOI: https://doi.org/10.1007/978-1-4684-5290-7_11
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