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Internalization of Hormone Receptor Complexes: Route and Significance

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Molecular and Cellular Aspects of Reproduction

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 205))

Abstract

Receptor-mediated endocytosis is a general process by which a wide variety of ligands are taken up with high specificity and affinity into cells. In this review we shall primarily discuss data in regard to the internalization of peptide hormones, especially insulin, but it is noteworthy that there are similarities as well as interesting differences by which membrane-bound lectins, immune complexes, viruses, toxins, etc. are handled by cells (Bergeron et al., 1985).

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Authors and Affiliations

  1. Departments of Medicine and Anatomy, McGill University, Montreal, Quebec, H3A 1A1, Canada

    Barry I. Posner, Masood N. Khan, Denis G. Kay & John J. M. Bergeron

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  1. Barry I. Posner
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  2. Masood N. Khan
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  3. Denis G. Kay
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  4. John J. M. Bergeron
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Editors and Affiliations

  1. Reproductive Biology Study Section, Division of Research Grants, National Institutes of Health, Westwood Building, Room 307, 20205, Bethesda, Maryland, USA

    Dharam S. Dhindsa D.V.M., Ph.D. (Executive Secretary/Referral Officer) (Executive Secretary/Referral Officer)

  2. Department of Biological Sciences, State University of New York, Cooke Hall 347, 14260, Buffalo, New York, USA

    Om P. Bahl Ph.D. (Professor of Biological Sciences) (Professor of Biological Sciences)

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© 1986 Plenum Press, New York

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Posner, B.I., Khan, M.N., Kay, D.G., Bergeron, J.J.M. (1986). Internalization of Hormone Receptor Complexes: Route and Significance. In: Dhindsa, D.S., Bahl, O.P. (eds) Molecular and Cellular Aspects of Reproduction. Advances in Experimental Medicine and Biology, vol 205. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5209-9_9

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  • DOI: https://doi.org/10.1007/978-1-4684-5209-9_9

  • Publisher Name: Springer, Boston, MA

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