Skip to main content
SpringerLink
Log in

The Interaction of Egg Peptides with Spermatozoa

  • Chapter
Molecular and Cellular Aspects of Reproduction

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 205))

Abstract

Mechanisms by which eggs (includes acellular matrices as well as other attached cells, such as cumulus oophorus cells) and/or other components of the female reproductive tract communicate with spermatozoa are beginning to be understood. Research has progressed to the molecular level in both invertebrates and vertebrates, and it can be anticipated that the genes responsible for the synthesis of some of the regulatory components will be soon identified and their function (or fate) in animals separated by large evolutionary distances determined.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ball, G. D., Bellin, M. E., Ax, R. L., and First, N. L., 1982, Glycosaminoglycans in bovine cumulus-oocyte complexes: Morphology and chemistry, Mol. Cell Endocrin., 28: 113–122.

    Article  CAS  Google Scholar 

  • Bedford, J. M., 1981, Why mammalian gametes don’t mix, Nature, 291: 286–288.

    Article  PubMed  CAS  Google Scholar 

  • Bedford, J. M., 1983, Significance of the need for sperm capacitation before fertilization in Eutherian mammals, Biol. Reprod., 28: 108–120.

    Article  CAS  Google Scholar 

  • Bentley, J. K., and Garbers, D. L., 1986a, Retention of the speract receptor by isolated plasma membranes of sea urchin spermatozoa, Biol. Reprod., 34: 413–421.

    Article  CAS  Google Scholar 

  • Bentley, J. K., and Garbers, D. L., 1986b, Isolation of spermatozoan plasma membranes which retain a functional receptor for resact, Cell, in press.

    Google Scholar 

  • Bentley, J. K., Garbers, D. L., Domino, S. E., Noland, T. D., VanDop, C., 1985, personal communication.

    Google Scholar 

  • Bleil, J. D., and Wassarman, P. M., 1980, Mammalian sperm-egg interaction: identification of a glycoprotein in mouse egg zonae pellucidae possessing receptor activity for sperm, Cell, 20: 873–882.

    Article  PubMed  CAS  Google Scholar 

  • Bleil, J. D., and Wassarman, P. M., 1983, Sperm-egg interactions in the mouse: Sequence of events and induction of the acrosome reaction by a zona pellucida glycoprotein, Dev. Biol., 95: 317–324.

    CAS  Google Scholar 

  • Dangott, L. J., and Garbers, D. L., 1984, Identification and partial characterization of the receptor for speract, J. Biol. Chem., 259: 13712–13716.

    PubMed  CAS  Google Scholar 

  • Florman, H. M., and Wassarman, P. M., 1985, O-linked oligosaccharides of mouse egg ZP3 account for its sperm receptor activity, Cell, 41:313–324.

    Article  PubMed  CAS  Google Scholar 

  • Foley, C. W., and Williams, W. L., 1967, Effect of bicarbonate and oviduct fluid on respiration of spermatozoa, Proc. Soc. Exp. Biol. Med., 126: 634–637.

    CAS  Google Scholar 

  • Garbers, D. L., and Kopf, G. S., 1980, The regulation of spermatozoa by calcium and cyclic nucleotides, Adv. Cyclic Nucleotide Res., 13: 251–306.

    CAS  Google Scholar 

  • Garbers, D. L., Kopf, G. S., Tubb, D. J., and Olson, G., 1983, Elevation of sperm adenosine 3’:5’-monophosphate concentrations by a fucose-sulfate-rich complex associated with eggs: I. Structural characterization, Biol. Reprod., 29: 1211–1220.

    Article  CAS  Google Scholar 

  • Garbers, D. L., Tubb, D. J., and Hyne, R. V., 1982a, A requirement of bicarbonate for Ca2+-induced elevations of cyclic AMP in guinea pig spermatozoa, J. Biol. Chem., 257: 8980–8984.

    CAS  Google Scholar 

  • Garbers, D. L., Watkins, H. D., Hansbrough, J. R.. Smith, A., and Misono, K.S., 1982b, The amino acid sequence and chemical synthesis of speract and of speract analogues, J. Biol. Chem., 257: 2734–2737.

    CAS  Google Scholar 

  • Glabe, C. G., 1985, Interaction of the sperm adhesive protein, bindin, with phospholipid vesicles. II. Bindin induces the fusion of mixed-phase vesicles that contain phosphatidylcholine and phosphatidylserine in vitro, J. Cell Biol., 100: 800–806.

    Article  PubMed  CAS  Google Scholar 

  • Glabe, C. G., Grabel, L. B., Vacquier, V. D., and Rosen, S. D., 1982, Carbohydrate specificity of sea urchin sperm bindin: A cell surface lectin mediating sperm-egg adhesion, J. Cell Biol., 94: 123–128.

    Article  PubMed  CAS  Google Scholar 

  • Glabe, C. G., and Lennarz, W. J., 1979, Species-specific sperm adhesion in sea urchins: A quantitative investigation of bindin mediated egg agglutination, J. Cell Biol., 83: 595–604.

    Article  PubMed  CAS  Google Scholar 

  • Glabe, C. G., and Vacquier, V. D., 1978, Egg surface glycoprotein receptor for sea urchin sperm bindin, Proc. Natl. Acad. Sci. USA, 75: 881–885.

    Article  PubMed  CAS  Google Scholar 

  • Gnessi, L., Ruff, M. R., Fraioli, F., and Pert, C.B., 1985, Demonstration of receptor-mediated chemotaxis by human spermatozoa: A novel quantitative bioassay, Exptl. Cell Res., 161: 219–230.

    Article  CAS  Google Scholar 

  • Gray, J. P., Drummond, G. I., Luk, D. W., Hardman, J. G., and Sutherland, E. W., 1976, Enzymes of vertebrate sperm, Arch. Biochem. Biophys., 172: 20–30.

    CAS  Google Scholar 

  • Hamner, C. E., and Williams, W. L., 1964, Identification of a sperm stimulating factor of rabbit oviduct fluid, Proc. Soc. Exp. Biol. Med., 117: 240–243.

    PubMed  CAS  Google Scholar 

  • Hansbrough, J. R., and Garbers, D. L., 1981, Purification and characterization of a peptide associtated with eggs that activates spermatozoa, J. Biol. Chem., 256: 1447–1452.

    PubMed  CAS  Google Scholar 

  • Hildebrandt, J. D., Codina, J., Tash, J. S., Kirchick, H. J., Lipschltz, L., Sekura, R. D., and Birnbaumer, L., 1985, The membrane-bound spermatozoal adenylyl cyclase system does not share coupling characteristics with somatic cell adenylyl cyclases, Endocrinology, 116: 1357–1366.

    Article  PubMed  CAS  Google Scholar 

  • Hyne, R. V., 1984, Bicarbonate-and calcium-dependent induction of rapid guinea pig sperm acrosome reactions by monovalent ionophores, Biol. Reprod., 31: 312–323.

    Article  CAS  Google Scholar 

  • Iqbal, M., Shivaji, S., Vijayasarathy, S., and Balaram, P., 1980, Synthetic peptides as chemoattractants for bull spermatozoa structure activity correlations, Biochem. Biophys. Res. Commun., 96: 235–242.

    CAS  Google Scholar 

  • Lenz, R. W., Ax, R. L., Grimek, H. J., and First, N. L., 1982, Proteoglycan from bovine follicular fluid enhances an acrosome reaction in bovine spermatozoa, Biochem. Biophys. Res. Commun., 106: 1092–1098.

    CAS  Google Scholar 

  • Lenz, R. W., Ball, G. D., Lohse, J. K., First, N. L., and Ax, R. L., 1983, Chondroitin sulfate facilitates an acrosome reaction in bovine spermatozoa as evidenced by light microscopy, electron microscopy, and in vitro fertilization, Biol. Reprod., 28: 683–690.

    Article  CAS  Google Scholar 

  • Lodge, J. R., and Salisbury, G. W., 1962, Initiation of anaerobic metabolism of mammalian spermatozoa by carbon dioxide, Nature, 195: 293–294.

    Article  PubMed  CAS  Google Scholar 

  • Meizel, S., and Turner, K. O., 1984, Glycosaminoglycans stimulate the acrosome reaction of previously capacitated hamster sperm, J. Cell Biol., 99: 261.

    Google Scholar 

  • Miller, R. L., 1982, Synthetic peptides are not chemoattractants for bull sperm, Gamete Res., 5: 395–402.

    Article  CAS  Google Scholar 

  • Mrsny, R. J., Waxman, L., and Meizel, S., 1979, Taurine maintains and stimulates motility of hamster sperm during capacitation in vitro, J. Exp. Zool., 210: 123–128.

    Article  PubMed  CAS  Google Scholar 

  • Murdoch, R. N., and Davis, W. D., 1978, Effects of bicarbonate on the respiration and glycolytic activity of boar spermatozoa, Aust. J. Biol. Sci., 31: 385–394.

    PubMed  CAS  Google Scholar 

  • Nomura, K.. and Isaka, S., 1985, Synthetic study on the structure-activity relationship of sperm activating peptides from the jelly coat of sea urchin eggs, Biochem. Biophys. Res. Commun., 126: 974–982.

    CAS  Google Scholar 

  • Nomura, K., Suzuki, N., Ohtake, H., and Isaka, S., 1983, Structure and action of sperm activity peptides from the egg jelly of a sea urchin, Anthocidaris crassispina, Biochem. Biophys. Res. Commun., 117: 147–153.

    CAS  Google Scholar 

  • Ohtake, H., 1976, Respiratory behavior of sea urchin spermatozoa. I. Effect of pH and egg water on the respiratory rate, J. Exp. Zool., 198: 303–312.

    CAS  Google Scholar 

  • Okamura, N., and Sugita, Y., 1983, Activation of spermatozoan adenylate cyclase by a low molecular weight factor in porcine seminal plasma, J. Biol. Chem., 258:13056–13062.

    PubMed  CAS  Google Scholar 

  • Okamura, N., Tajima, Y., Soejima, A., Masuda, H., and Sugita, Y., 1985, Sodium bicarbônate in seminal plasma stimulates the motility of mammalian spermatozoa through direct activation of adenylate cyclase, J. Biol. Chem., 260: 9699–9705.

    PubMed  CAS  Google Scholar 

  • Ramarao, C. S., and Garbers, D. L., 1985, Receptor-mediated regulation of guanylate cyclase activity in spermatozoa, J. Biol. Chem., 260: 8390–8396.

    PubMed  CAS  Google Scholar 

  • Repaske, D. R., and Garbers, D, L., 1983, A hydrogen ion flux mediates stimulation of respiratory activity by speract in sea urchin spermatozoa, J. Biol. Chem., 258: 6025–6029.

    PubMed  CAS  Google Scholar 

  • Rossignol, D. P., Earles, B. J., Decker, G. L., and Lennarz, W. J., 1984, Characterization of the sperm receptor on the surface of the eggs of Strongylocentrotus purpuratus, Dev. Biol., 104: 308–321.

    CAS  Google Scholar 

  • Saling, P. M., Storey, B. T., Wolf, D. P., 1978, Calcium-dependent binding of mouse epididymal spermatozoa to the zona pellucida, Dev. Biol., 65: 515–525.

    CAS  Google Scholar 

  • SeGall, G. K., and Lennarz, W. J., 1979, Chemical characterization of the component of the jelly coat from sea urchin eggs responsible for induction of the acrosome reaction, Dev. Biol., 71: 33–48.

    CAS  Google Scholar 

  • SeGall, G. K., and Lennarz, W. J., 1981, Jelly coat and induction of the acrosome reaction in echinoid sperm, Dev. Biol., 86: 87–93.

    CAS  Google Scholar 

  • Shimomura, H., and Garbers, D. L., 1985, Differential effects of resact analogues on sperm respiration rates and cyclic nucleotide concentrations, submitted.

    Google Scholar 

  • Singh, J. P., Babcock, D. F., and Lardy, H. A., 1978, Increased calcium-ion influx is a component of capacitation of spermatozoa, Biochem. J., 172: 549–556.

    PubMed  CAS  Google Scholar 

  • Smith, A. C., and Garbers, D. L., 1983, The binding of an 1251-speract analogue to spermatozoa, in: “Biochemistry of Metabolic Processes,” D. L. F. Lennon, F. W. Stratman, and R. N. Zahlten, eds., Elsevier Science Pub. Co., New York, pp. 15–28.

    Google Scholar 

  • Storey, B. T., Lee, M. A., Muller, C., Ward, C. R., and Wirtshafter, D. G., 1984, Binding of mouse spermatozoa to the zonae pellucidae of mouse eggs in cumulus: Evidence that the acrosomes remain substantially intact, Biol. Reprod., 31: 1119–1128.

    Article  CAS  Google Scholar 

  • Suzuki, N., Nomura, K., Ohtake, H., and Isaka, S., 1981, Purification and the primary structure of sperm-activating peptides from jelly coat of sea urchin eggs, Biochem. Biophys. Res. Commun., 99:1238–1244.

    Article  PubMed  CAS  Google Scholar 

  • Suzuki, N., Shimomura, H., Radany, E. W., Ramarao, C. S., Ward, G. E., Bentley, J. K., and Garbers, D. L., 1984, A peptide associated with eggs causes a mobility shift in a major plasma membrane protein of spermatozoa, J. Biol. Chem., 259: 14874–14879.

    PubMed  CAS  Google Scholar 

  • Takai, K., Kurashina, Y., Suzuki-Hori, C., Okamota, H., and Hayaishi, O., 1974, Adenylate cyclase from Brevibacterium liquefaciens, I. Purification crystallization, and some properties, J. Biol. Chem., 249: 1965–1972.

    CAS  Google Scholar 

  • Talbot, P., 1984, Hyaluronidase dissolves a component in the hamster zona pellucida, J. Exp. Zool., 229: 309–316.

    Article  PubMed  CAS  Google Scholar 

  • Vacquier, V. D., 1979, The fertilizing capacity of sea urchin sperm rapidly decreases after induction of the acrosome reaction, Dev. Growth Differ., 21: 61–60.

    Article  Google Scholar 

  • Vacquier, V. D., 1983, Purification of sea urchin sperm bindin by DEAEcellulose chromatography, Anal. Biochem., 129: 497–501.

    CAS  Google Scholar 

  • Vacquier, V. D., and Moy, G. W., 1977, Isolation of bindin: The protein responsible for adhesion of sperm to sea urchin eggs, Proc. Natl. Acad. Sci. USA, 74: 2456–2460.

    Article  PubMed  CAS  Google Scholar 

  • Vijayaraghavan, S., Critchlow, L. M., and Hoskins, D. D., 1985, Evidence for a role for cellular alkalinization in the cyclic adenosine 3’,5’-monophosphate-mediated initiation of motility in bovine caput spermatozoa, Biol. Reprod., 32: 489–500.

    Article  CAS  Google Scholar 

  • Vijayasarathy, S., Shivaji, S., Iqbal, M., and Balaram, P., 1980, FormylMet-Leu-Phe induces chemotaxis and acrosomal enzyme release in bull sperm, FEBS Lett., 115: 178–180.

    Article  PubMed  CAS  Google Scholar 

  • Ward, G. E., Brokaw, C. J., Garbers, D. L., and Vacquier, V. D., 1985a, Chemotaxis of Arbacia punctulata spermatozoa to resact, a peptide from the egg jelly layer, J. Cell Biol., 101: 2324–2329.

    Article  CAS  Google Scholar 

  • Ward, G. E., Garbers, D. L., and Vacquier, V. D., 1985b, Effects of extracellular egg factors on sperm guanylate cyclase, Science, 227: 768–770.

    Article  CAS  Google Scholar 

  • Ward, G. E., and Vacquier, V. D., 1983, Dephosphorylation of a major sperm membrane protein is induced by egg jelly during sea urchin fertilization, Proc. Natl. Acad. Sci., 80: 5578–5582.

    Article  PubMed  CAS  Google Scholar 

  • Wassarman, P. M., 1983, Fertilization in: “Cell Interactions and Development: Molecular Mechanisms,” K. Yamada, ed., Wiley, New York, pp. 1–27.

    Google Scholar 

  • Yanagimachi, R., 1981, Mechanisms of fertilization in mammals, in: “Fertilization and Embryonic Development In vitro,” L. M. Mastroianni, and J. D. Biggers, eds., Plenum, New York, pp. 81–182.

    Chapter  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Howard Hughes Medical Institute and the Departments of Pharmacology and Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, 37232, USA

    David L. Garbers, Thomas D. Noland, Lawrence J. Dangott, Chodavarapu S. Ramarao & J. Kelley Bentley

Authors
  1. David L. Garbers
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Thomas D. Noland
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Lawrence J. Dangott
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Chodavarapu S. Ramarao
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. J. Kelley Bentley
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Reproductive Biology Study Section, Division of Research Grants, National Institutes of Health, Westwood Building, Room 307, 20205, Bethesda, Maryland, USA

    Dharam S. Dhindsa D.V.M., Ph.D. (Executive Secretary/Referral Officer) (Executive Secretary/Referral Officer)

  2. Department of Biological Sciences, State University of New York, Cooke Hall 347, 14260, Buffalo, New York, USA

    Om P. Bahl Ph.D. (Professor of Biological Sciences) (Professor of Biological Sciences)

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Plenum Press, New York

About this chapter

Cite this chapter

Garbers, D.L., Noland, T.D., Dangott, L.J., Ramarao, C.S., Bentley, J.K. (1986). The Interaction of Egg Peptides with Spermatozoa. In: Dhindsa, D.S., Bahl, O.P. (eds) Molecular and Cellular Aspects of Reproduction. Advances in Experimental Medicine and Biology, vol 205. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5209-9_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-5209-9_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5211-2

  • Online ISBN: 978-1-4684-5209-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation