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Do Motor Neurons Contain Functional Prejunctional Cholinoceptors?

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Dynamics of Cholinergic Function

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 30))

Abstract

Among the many mechanisms which may regulate acetylcholine (ACh) release from mammalian motor nerve terminals is the possibility of negative feedback by the neurotransmitter itself on prejunctional cholinoceptor sites. Autoregulation of neurotransmitter release has been documented in adrenergic systems (21) and in central and autonomic cholinergic systems (12, 15, 22). Negative feedback of released ACh through presynaptic muscarinic receptors has been shown in cerebral cortex (22), hippocampus (15), guinea pig ileum (12), sympathetic ganglion of the bull frog (13) and rat atrium (24).

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© 1986 Plenum Press, New York

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Bierkamper, G.G., Aizenman, E., Millington, W.R. (1986). Do Motor Neurons Contain Functional Prejunctional Cholinoceptors?. In: Hanin, I. (eds) Dynamics of Cholinergic Function. Advances in Behavioral Biology, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5194-8_43

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  • DOI: https://doi.org/10.1007/978-1-4684-5194-8_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5196-2

  • Online ISBN: 978-1-4684-5194-8

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