Abstract
Hypothermia is firmly established as a therapeutic measure in open heart surgery. The effects of hypothermia on the body were noted as early as 1798 when James Currie of Liverpool treated patients with fever by cooling them to 32°C. Observations on the effect of body cooling on animals were made during the 19th and early 20th century by Claude Bernhard. Smith and Fay (1940) demonstrated the analgesic effects of hypothermia in the cancer patient. Bigelow et al (1950) cooled dogs by surface immersion in cold water to below 25°C and maintained circulatory arrest for 15 minutes. The introduction of cardiopulmonary bypass in the 1950’s, enabled rapid safe cooling of the patient; hypothermia was perfected for clinical use during cardiac surgery by Swan (1984).
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© 1986 Plenum Press, New York
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Fennema, M., Prakash, O., Dhasmana, M., Faithfull, S., Erdmann, W. (1986). Changes in Intramyocardial Oxygen Tensions during Hypothermia in Pigs. In: Longmuir, I.S. (eds) Oxygen Transport to Tissue VIII. Advances in Experimental Medicine and Biology, vol 200. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5188-7_43
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DOI: https://doi.org/10.1007/978-1-4684-5188-7_43
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