Abstract
As our experimental set-up for continuous recording of local blood flow in the cerebral cortex of a laboratory animal with chronically implanted miniature thermistors (based on the heat clearance principle) gave satisfactory results for routine tests of pharmacological agents during anoxia, hypoxia, hypercapnia, etc., experiments, we intended to standardize the apparatus, to increase accuracy, to facilitate calibration and to enhance flexibility with respect to the operator.
The exponential aspect in the thermistor resistance/temperature characteristic is linearized by applying a logarithmic converter in the thermistor amplifier. Calibration to the centigrade temperature scale is performed by a three digit numerical adaptation of two thermistor constants determined in a thermostatic-cryostatic bath (zero and slope). A heating power measuring circuit is provided so that the dissipation constant of the thermistor implanted in tissue can be obtained and the thermal conductivity of the tissue can be estimated.
Linearity of the relation between cooling of the heated thermistor and local flow, for small cooling values as they are registered in vivo, is still being investigated.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Coremans, J., Vermariƫn, H., Vereecke, F., and Bourgain, R.H., in press, Assessment of the in vivo recording of local cerebral blood flow using a thermistor device, in: Oxygen Transport to Tissue, Plenum, New York.
Sachse, H.B., 1975, Semiconducting temperature sensors and their applications, John Wiley.
Van Waeyenberge, M., Vermariƫn, H., De Backer, H., Manil, J. and Bourgain, R.H., in press, Discriminant parameters representing cerebral function during anoxic anoxia investigations, in: Oxygen Transport to Tissue, Plenum, New York.
Vermariƫn, H., Coremans, J., Vereecke, F., and Bourgain, R.H., 1985, A thermistor device for the continuous recording of mass transport velocity in tissue based on the heat clearance principle, in: Oxygen Transport to Tissue VI, D. Bruley, H.I. Bicher and D. Reneau, eds., Plenum, New York.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
Ā© 1986 Plenum Press, New York
About this chapter
Cite this chapter
Vermariƫn, H., Coremans, J., Vereecke, F., Bourgain, R.H. (1986). Standardization of a Device for Continuous Observation of Local Flow in Tissue. In: Longmuir, I.S. (eds) Oxygen Transport to Tissue VIII. Advances in Experimental Medicine and Biology, vol 200. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5188-7_20
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5188-7_20
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5190-0
Online ISBN: 978-1-4684-5188-7
eBook Packages: Springer Book Archive