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Hepatic Functions in Health and Disease: Implications in Drug Carrier Use

  • Chapter
Targeting of Drugs With Synthetic Systems

Part of the book series: NATO ASI Series ((NSSA,volume 113))

Abstract

The liver is an unusual organ in that it receives blood not only from the aorta but an even larger amount via the portal vein, the main vein draining the intestine, spleen and pancreas. The arterial blood and portal venous blood mingle within the liver and return to the heart via the hepatic veins and inferior vena cava. The liver receives in total about a quarter of the output of the heart, but only 20–25% of it is arterial blood.

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Author information

Authors and Affiliations

  1. Academic Department of Medicine, Royal Free Hospital, London, NW3 2QG, UK

    Neil McIntyre

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  1. Neil McIntyre
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Editors and Affiliations

  1. Royal Free Hospital School of Medicine, London, England

    Gregory Gregoriadis  & Judith Senior  & 

  2. Smith Kline & French Laboratories, Philadelphia, Pennsylvania, USA

    George Poste

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© 1986 Plenum Press, New York

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McIntyre, N. (1986). Hepatic Functions in Health and Disease: Implications in Drug Carrier Use. In: Gregoriadis, G., Senior, J., Poste, G. (eds) Targeting of Drugs With Synthetic Systems. NATO ASI Series, vol 113. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5185-6_7

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  • DOI: https://doi.org/10.1007/978-1-4684-5185-6_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5187-0

  • Online ISBN: 978-1-4684-5185-6

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