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Amniocentesis

  • Chapter
Genetic Disorders and the Fetus

Abstract

Amniocentesis is a surgical technique that has been used for a variety of indications. The procedure was first utilized in Germany in the early 1880s to treat polyhydramnios (Lambl, 1881; Schatz, 1882). In 1930, Menées et al. (1930) used amniocentesis to inject contrast media into the amniotic sac in order to evaluate the fetus and localize the placenta. The procedure of using amniocentesis to introduce hypertonic saline into the amniotic sac for pregnancy termination made its appearance in 1937 (Aburel, 1937). Amniocentesis utilization increased rapidly in the 1950s, when spectrophotometric analysis of bilirubin proved valuable in monitoring fetuses with Rh isoimmunization (Bevis, 1952; Walker, 1957).

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  1. Department of Obstetrics and Gynecology, Division of Reproductive Genetics, The University of Tennessee College of Medicine, 38163, Memphis, Tennessee, USA

    Sherman Elias & Joe Leigh Simpson

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  1. Center for Human Genetics, Boston University School of Medicine, Boston, Massachusetts, USA

    Aubrey Milunsky MB.B.Ch., D.Sc., F.R.C.P., D.C.H. (Professor of Pediatrics, Obstetrics and Gynecology, and Pathology, Director) (Professor of Pediatrics, Obstetrics and Gynecology, and Pathology, Director)

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© 1986 Aubrey Milunsky

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Elias, S., Simpson, J.L. (1986). Amniocentesis. In: Milunsky, A. (eds) Genetic Disorders and the Fetus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5155-9_2

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