Abstract
There has been a great deal of attention directed toward the source, regulation, and function of the peptides derived from the 31 -kD proadrenocorticotropin-endorphin precursor in the pituitary (Barker, 1977; Krieger, 1980; Numa and Nakanishi, 1980). The parent molecule is metabolized to an amino-terminal segment, referred to as the 16K fragment, the 39-amino-acid hormone ACTH, and a 91-amino-acid peptide, β-lipotropin (β-LPH). In turn, ACTH and β-LPH may be metabolized to the smaller peptides, including α-melanotropin (α-MSH) from ACTH and β-MSH and βendorphin from β-lipotropin.
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© 1986 Plenum Press, New York
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Vahouny, G.V., Herron, C., Tombes, R., Moody, T.W. (1986). Neuropeptides and Adrenal Steroidogenesis. In: Moody, T.W. (eds) Neural and Endocrine Peptides and Receptors. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5152-8_42
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DOI: https://doi.org/10.1007/978-1-4684-5152-8_42
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