Histocompatibility and Reproduction

  • Susan Heyner
Part of the Reproductive Biology book series (RBIO)


In all outbreeding populations, fetal and maternal tissues are in intimate juxtaposition, and there is ample evidence to show that the maternal organism responds immunologically to the paternally derived histocompatibility antigens of the fetus (reviewed by Head and Billingham, 1983). This situation has led a number of biologists to consider the fetus as an allograft, and to propose various mechanisms whereby the fetus evades immunological rejection (Medawar, 1953).


Migration Inhibitory Factor Mouse Oocyte Histocompatibility Antigen Major Histocompatibility Complex Antigen Early Mouse Embryo 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Susan Heyner
    • 1
  1. 1.Department of Obstetrics and GynecologyAlbert Einstein Medical Center, Northern DivisionPhiladelphiaUSA

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