Anti-GnRH Monoclonals: Pituitary and Extrapituitary Actions in Control of Fertility

  • C. Das
  • S. K. Gupta
  • A. Malik
  • G. P. Talwar
Part of the Reproductive Biology book series (RBIO)


The decapeptide gonadotropin releasing hormone (GnRH) has a pivotal role in control of both male and female fertility. It is one of those molecules which has been conserved through evolution. The primary amino acid sequence of the hormone from ovine and. porcine sources is identical to that of human. The peptide controls the secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the pituitary and the same molecule is biologically active in a large number of species (Schally et al, 1973).


Luteinizing Hormone Thyroid Stimulate Hormone Ascites Fluid Luteinizing Hormone Release Hormone Marmoset Monkey 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • C. Das
    • 1
  • S. K. Gupta
    • 2
  • A. Malik
    • 1
  • G. P. Talwar
    • 2
  1. 1.Department of BiochemistryAll India Institute of Medical SciencesNew DelhiIndia
  2. 2.National Institute of ImmunologyNew DelhiIndia

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