The Potential Effectiveness and Safety of Second Generation Vaccines

  • John D. Biggers
Part of the Reproductive Biology book series (RBIO)


Several times during this symposium on Immunological Approaches to Contraception and Promotion of Fertility, reference has been made to second generation vaccines (Talwar, 1985). A characteristic of these vaccines is that they simultaneously attack more than one vulnerable site. Intuitively it seems obvious that such a strategy should result in greater efficiency of the vaccine. The magnitude of the gain in efficiency to be expected is less obvious because it will be strongly influenced by the correlations between the effects of the different components.


Reproductive Biology Zona Pellucida Contraceptive Agent Mouse Ovum Human Fertility 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • John D. Biggers
    • 1
  1. 1.Laboratory of Human Reproduction and Reproductive Biology and Department of Physiology and BiophysicsHarvard Medical SchoolBostonUSA

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