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Immunization Against LHRH Without the Use of Freund’s Complete Adjuvant

  • C. Shaha
  • S. Kaul
  • M. Kini
  • M. Chowdhury
  • R. Anand
  • C. Das
  • G. P. Talwar
Chapter
Part of the Reproductive Biology book series (RBIO)

Abstract

Neutralization of endogenous LHRH by active immunization has been reported in several species including rodents (Fraser et al, 1974) and monkeys (Chappel et al, 1980). Antibodies to LHRH inhibit LHRH presumably at the level of portal blood vessels before the hormone reaches the pituitary. Due to interception of LHRH, no LH or FSH is released thereby disrupting the production of testicular steroids and subsequently spermatogenesis in the male.

Keywords

Luteinizing Hormone Seminiferous Tubule Tetanus Toxoid Luteinizing Hormone Release Hormone Muramyl Dipeptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • C. Shaha
    • 1
  • S. Kaul
    • 1
  • M. Kini
    • 1
  • M. Chowdhury
    • 1
  • R. Anand
    • 1
  • C. Das
    • 1
  • G. P. Talwar
    • 1
  1. 1.National Institute of ImmunologyNew DelhiIndia

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