Cloning and Expression of Lutropin Genes
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In man, lutropin (LH) and chorionic gonadotropin (CG) belong to a group of hormones known collectively as the glycoprotein hormones. LH along with follicle-stimulating hormone (follitropin, FSH) and thyroid-stimulating hormone (TSH) is produced and secreted by the anterior pituitary gland and CG by the placenta. LH and FSH, the pituitary gonadotropins, stimulate the production of the sex steroid hormones and gametogenesis. As such, they are important for sexual development and function, and reproduction. CG, whose maximal levels appear in early pregnancy, is essential for the function of the corpus luteum (1, 2).
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