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Cloning and Expression of Lutropin Genes

  • William W. Chin
  • Soheyla D. Gharib
Chapter
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Part of the Reproductive Biology book series (RBIO)

Abstract

In man, lutropin (LH) and chorionic gonadotropin (CG) belong to a group of hormones known collectively as the glycoprotein hormones. LH along with follicle-stimulating hormone (follitropin, FSH) and thyroid-stimulating hormone (TSH) is produced and secreted by the anterior pituitary gland and CG by the placenta. LH and FSH, the pituitary gonadotropins, stimulate the production of the sex steroid hormones and gametogenesis. As such, they are important for sexual development and function, and reproduction. CG, whose maximal levels appear in early pregnancy, is essential for the function of the corpus luteum (1, 2).

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • William W. Chin
    • 1
    • 2
    • 3
  • Soheyla D. Gharib
    • 1
    • 2
    • 3
  1. 1.Department of MedicineBrigham and Women’s HospitalUSA
  2. 2.Howard Hughes Medical Institute LaboratoriesUSA
  3. 3.Section on Molecular GeneticsJoslin Diabetes CenterBostonUSA

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