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Cell Lineage and Cell Interactions in the Determination of Developmental Cell Fates

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Genetics, Development, and Evolution

Part of the book series: Stadler Genetics Symposia Series ((SGSS))

Abstract

A central problem of developmental biology is to understand the sequence of cellular and molecular events which transforms a fertilized egg into a mature organism composed of a precise spatial array of distinct cell types. A significant consideration in addressing this problem is the fact that each of the many cells in the mature organism is descended from the egg via a lengthy sequence of progenitor cell divisions. In order to reduce the number of variables associated with the problem, many embryologists have concentrated on invertebrates such as nematodes, annelids, molluscs and tunicates in which the sequence of embryonic cell divisions is highly stereotyped. Because of this regularity it is possible to portray the development of the entire organism by the genealogical relationship between the composite cells, and to identify individual cells on the basis of their lineage (Zur Strassen, 1896; Conklin, 1905; Schleip, 1936).

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© 1986 Plenum Press, New York

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Shankland, M., Stent, G.S. (1986). Cell Lineage and Cell Interactions in the Determination of Developmental Cell Fates. In: Gustafson, J.P., Stebbins, G.L., Ayala, F.J. (eds) Genetics, Development, and Evolution. Stadler Genetics Symposia Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5137-5_10

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  • DOI: https://doi.org/10.1007/978-1-4684-5137-5_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5139-9

  • Online ISBN: 978-1-4684-5137-5

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