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Effect of Calcium Antagonists on Vasopressin Induced Changes in Myocardial and Renal Pyridine Nucleotides in the Intact Rat

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Myocardial and Skeletal Muscle Bioenergetics

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 194))

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Abstract

Recent experimental interest has centered on the role of the calcium antagonists in the preservation of tissue function due to their ability to inhibit intracellular calcium accumulation as well as their potent vasodilatory properties. Most studies to date have centered primarily on myocardial tissue rendered either ischemic or anoxic by coronary artery ligation or manipulation of perfusing solutions. Assessment of myocardial function has included the quantitation of infarct size,1 ultrastructural histologic changes,2 or the evaluation of cellular biochemical parameters such as measurement of high energy phosphates,3 intracellular pH,4 and pyridine nucleotides.5

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Authors and Affiliations

  1. Department of Medicine, Allegheny-Singer Research Institute, Allegheny General Hospital, Pittsburgh, PA, USA

    D. DiPette, R. Townsend, J. Guntipalli, K. Simpson, A. Rogers & E. Bourke

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  1. D. DiPette
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  2. R. Townsend
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  3. J. Guntipalli
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  4. K. Simpson
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  5. A. Rogers
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  6. E. Bourke
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Editors and Affiliations

  1. University of Southern California School of Medicine and Hollywood Presbyterian Medical Center, Los Angeles, California, USA

    Nachman Brautbar

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© 1986 Plenum Press, New York

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DiPette, D., Townsend, R., Guntipalli, J., Simpson, K., Rogers, A., Bourke, E. (1986). Effect of Calcium Antagonists on Vasopressin Induced Changes in Myocardial and Renal Pyridine Nucleotides in the Intact Rat. In: Brautbar, N. (eds) Myocardial and Skeletal Muscle Bioenergetics. Advances in Experimental Medicine and Biology, vol 194. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5107-8_38

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  • DOI: https://doi.org/10.1007/978-1-4684-5107-8_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5109-2

  • Online ISBN: 978-1-4684-5107-8

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