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Movement Disorders pp 205–226Cite as

Treatments for Tardive Dyskinesia

An Overview of Noncatecholaminergic/Noncholinergic Treatments

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Abstract

Since the late 1960s, tardive dyskinesia (TD) has been recognized as a potential sequela of prolonged therapy with neuroleptics. Besides the disfiguring movements that characterize this syndrome, TD is frequently complicated by ternperomandibular joint dysfunction, mouth ulcers, accidental trauma secondary to position instability, respiratory problems, and speech pathology. The movements themselves are often a source of social embarrassment and tend to further isolate individuals with concomitant disabling illnesses like schizophrenia. Because of its medical, social, and legal implications, TD is one of the most significant complications of pharmacological treatment for psychiatric illnesses. As a result, considerable effort has been devoted to finding a treatment for its various symptoms; however, no universally successful therapy has yet been demonstrated.

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Authors and Affiliations

  1. Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore, Maryland, 21228, USA

    Larry D. Alphs

  2. Illinois State Psychiatric Institute, Chicago, Illinois, 60612, USA

    John M. Davis

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  1. Larry D. Alphs
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Editors and Affiliations

  1. Ensor Foundation Research Laboratory, William S. Hall Psychiatric Institute, Columbia, South Carolina, USA

    Nandkumar S. Shah Ph.D. (Director, Research Professor) (Director, Research Professor)

  2. Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, Columbia, South Carolina, USA

    Nandkumar S. Shah Ph.D. (Director, Research Professor) & Alexander G. Donald M.D. (Director, Professor and Chairman) (Director, Research Professor) &  (Director, Professor and Chairman)

  3. William S. Hall Psychiatric Institute, Columbia, South Carolina, USA

    Alexander G. Donald M.D. (Director, Professor and Chairman) (Director, Professor and Chairman)

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© 1986 Plenum Publishing Corporation

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Alphs, L.D., Davis, J.M. (1986). Treatments for Tardive Dyskinesia. In: Shah, N.S., Donald, A.G. (eds) Movement Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5038-5_11

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  • DOI: https://doi.org/10.1007/978-1-4684-5038-5_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5040-8

  • Online ISBN: 978-1-4684-5038-5

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