Enzyme Mediated Immunoassay: An Overview

  • T. T. Ngo


Since its introduction by Yalow and Berson (1959), radioimmunoassay (RIA) has played important roles in facilitating and accelerating basic discoveries in biomedical sciences and has become a standard tool in laboratory medicine. Millions of clinical tests are now routinely performed by using RIA. The rapid and wide acceptance of RIA as a routine clinical method can be attributed to (1) the general applicability of the method, i.e., any compound can be analyzed by a RIA so long as an antibody specific to that compound is available; (2) the selectivity and specificity of the method; (3) the sensitivity of a radioactive isotope as the label in RIA and (4) the minimal inference and ease of performing the test.


Enzyme Immunoassay Flavin Adenine Dinucleotide Flavin Adenine Dinucleotide Immobilize Antibody Enzyme Modulator 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • T. T. Ngo
    • 1
  1. 1.Department of Developmental and Cell BiologyUniversity of CaliforniaIrvineUSA

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