Abstract
Since its introduction by Yalow and Berson (1959), radioimmunoassay (RIA) has played important roles in facilitating and accelerating basic discoveries in biomedical sciences and has become a standard tool in laboratory medicine. Millions of clinical tests are now routinely performed by using RIA. The rapid and wide acceptance of RIA as a routine clinical method can be attributed to (1) the general applicability of the method, i.e., any compound can be analyzed by a RIA so long as an antibody specific to that compound is available; (2) the selectivity and specificity of the method; (3) the sensitivity of a radioactive isotope as the label in RIA and (4) the minimal inference and ease of performing the test.
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Ngo, T.T. (1985). Enzyme Mediated Immunoassay: An Overview. In: Ngo, T.T., Lenhoff, H.M. (eds) Enzyme-Mediated Immunoassay. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5012-5_2
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DOI: https://doi.org/10.1007/978-1-4684-5012-5_2
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