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Gene Transfer with Retrovirus Vectors

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Genetic Engineering: Principles and Methods

Part of the book series: Genetic Engineering: Principles and Methods ((GEPM,volume 7))

Abstract

The ability to introduce new genetic information into animal cells has opened up the possibility of functionally analyzing the regulatory or coding capacity of cloned DNA fragments. This, in turn, has also facilitated the development of techniques for the molecular cloning of eukaryotic genes on the basis of their ability to alter the phenotype of the recipient cell. Thus, there is now considerable interest in the development of improved methods of gene transfer, applicable to a wide range of cell types both in cell culture and the intact animal.

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Bernstein, A., Berger, S., Huszar, D., Dick, J. (1985). Gene Transfer with Retrovirus Vectors. In: Setlow, J.K., Hollaender, A. (eds) Genetic Engineering: Principles and Methods. Genetic Engineering: Principles and Methods, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4973-0_11

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  • DOI: https://doi.org/10.1007/978-1-4684-4973-0_11

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