Abstract
The development by Mishell and Dutton of a culture technique for immunization of mouse spleen cells (Mishell and Dutton, 1967) was an important advance in the study of the humoral immune response since it provided a convenient and versatile way to study cellular and subcellular events in the response.
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© 1985 Plenum Press, New York
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Hoffmann, M.K., Hirst, J.A. (1985). Principles of in Vitro Immunization of Human B Lymphocytes. In: Engleman, E.G., Foung, S.K.H., Larrick, J.W., Raubitschek, A.A. (eds) Human Hybridomas and Monoclonal Antibodies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4949-5_16
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DOI: https://doi.org/10.1007/978-1-4684-4949-5_16
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