Abstract
The induction of hypovolemia within an organism triggers off many, closely associated processes whereby individual details of their spatial and temporal interactions are not yet fully understood. The most important primary responses to hypovolemia are:
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reduction in the transport of O2 and CO2 molecules
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decrease in velocity of capillary flow as a consequence of the resulting hypotension
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change in capillary perfusion pattern of the various organs.
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References
Eklöf, B., Macmillan, V., and Siesjö, B. L., 1972, Cerebral energy state and cerebral venous PO2 in experimental hypotension caused by bleeding, Acta Physiol. Scand. 86:515–527.
Fitts, C. T., Bicher, H. I., and Yarbrough III, D. R., 1973, Blood and tissue oxygenation during hemorrhagic shock as determined with ultra micro oxygen electrodes, Adv. Exp. Med. Biol. 37A:477–489.
Kovách, A. G. B., 1973, Tissue blood flow and metabolism in control and phenoxybenzamine-pretreated animals in experimental shock, in: “Traumatic Shock”, G. Y. Szánta, W. Honig, O. Székely, ed., Akadémiai Kiadó, Budapest, pp. 163–185.
Metzger, H., Erdmann, W., and Thews, G., 1971, Effect of short periods of hypoxia, hyperoxia and hypercapnia on brain O2 supply, J. Appl. Physiol. 31:751–759.
Metzger, H., and Heuber, S., 1977, Local oxygen tension and spike activity of the cerebral grey matter of the rat and its response to short intervals of O2 deficiency or CO2 excess, Pflügers Arch. 370:201–209.
Metzger, H., Heuber-Metzger, S., Steinacker, A., and Strüber, J., 1980, Staining PO2 measurement sites in the rat brain cortex and quantitative morphometry of the surrounding capillaries, Pflügers Arch.388: 21–27.
Silver, L. A., 1978, Extracellular oxygen gradients in shock, in: “Frontiers of Biological Energetics”, P. I. Dutten, J. S. Leigh, A. Scarpa, ed., Academic Press, New York, pp. 1435–1443.
Scherf, M., Oestern, H. J., and Metzger, H., in preparation, Studies of hemorrhagic and traumatic shock influence on liver oxygen tension. Effects of a single large dose of dexamethasone, submitted to Adv. Exp. Med. Biol.
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© 1984 Plenum Press, New York
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Metzger, H., Heuber-Metzger, S. (1984). The Hypoxic Response to Hypovolemia. In: Bruley, D., Bicher, H.I., Reneau, D. (eds) Oxygen Transport to Tissue—VI. Advances in Experimental Medicine and Biology, vol 180. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4895-5_58
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DOI: https://doi.org/10.1007/978-1-4684-4895-5_58
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