Abstract
Even though renal blood flow is re-established after ischemia in the rat kidney, a cellular swelling, particularly in the straight portion of the proximal tubule, persists and an early, important step in the development of acute tubular necrosis is established (Frega et al., 1976; 1979). This ischemic cell-swelling, due to an unbalanced osmotic activity of intracellular macromolecules, may be counteracted by a reduction of the transmembrane gradients for sodium and potassium ions and by the presence of poorly permeable molecules in the inter-stitium (Sacks et al., 1971; Frega et al., 1979).
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© 1984 Plenum Press, New York
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Gronow, G.H.J., Benk, P., Franke, H. (1984). Effects of Anaerobic Substrates on Post-Anoxic Cellular Functions in Isolated Tubular Segments of Rat Kidney Cortex. In: Bruley, D., Bicher, H.I., Reneau, D. (eds) Oxygen Transport to Tissue—VI. Advances in Experimental Medicine and Biology, vol 180. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4895-5_38
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DOI: https://doi.org/10.1007/978-1-4684-4895-5_38
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