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Computer Controlled Blood Pressure Changes Required for Steady State Oxygen Control of Partial Ischemia in the Rat Brain Cortex

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Oxygen Transport to Tissue—VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 180))

Abstract

We have been interested in determining the duration and severity of ischemia necessary to injure cerebral cortical neurons. In preliminary experiments in the monkey, we had noticed that the earliest histological change is vacuolation of dendrites followed by progressive vacuolation in the cell body.1

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Reference

  1. J.H. Garcia, H.L. Mitchem, L. Briggs, R. Morawetz, A.G. Hudetz, J.B. Hazelrig, J. Halsey, K. Conger. Transient focal ischemia in subhuman primates. J. Neuropath. Exper. Neurol. 42:44–60 (1983).

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Author information

Authors and Affiliations

  1. University of Alabama Medical Center, University Station, Birmingham, AL, 35294, USA

    K. A. Conger, H. P. Moraes, E. R. Strong, K. Hino, L. Briggs, J. H. Garcia & J. H. Halsey Jr.

Authors
  1. K. A. Conger
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  2. H. P. Moraes
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  3. E. R. Strong
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  4. K. Hino
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  5. L. Briggs
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  6. J. H. Garcia
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  7. J. H. Halsey Jr.
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Editor information

Editors and Affiliations

  1. California Polytechnic State University, San Luis Obispo, California, USA

    Duane Bruley

  2. Western Tumor Medical Group, Van Nuys, California, USA

    Haim I. Bicher

  3. Louisiana Tech University, Ruston, Louisiana, USA

    Daniel Reneau

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© 1984 Plenum Press, New York

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Conger, K.A. et al. (1984). Computer Controlled Blood Pressure Changes Required for Steady State Oxygen Control of Partial Ischemia in the Rat Brain Cortex. In: Bruley, D., Bicher, H.I., Reneau, D. (eds) Oxygen Transport to Tissue—VI. Advances in Experimental Medicine and Biology, vol 180. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4895-5_22

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  • DOI: https://doi.org/10.1007/978-1-4684-4895-5_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4897-9

  • Online ISBN: 978-1-4684-4895-5

  • eBook Packages: Springer Book Archive

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