An Isolated Rat Brain Preparation Perfused with a Fluorocarbon Emulsion

  • Josef Krieglstein
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 180)


Cerebral metabolism and blood flow have frequently been examined in intact animals. An isolated brain preparation, however, offers essential advantages since the activity of the organ is not affected by secondary peripheral actions such as cardiovascular or respiratory effects or liver and muscle metabolism. Furthermore, a perfusion medium can be used permitting an absolute control of the arterial supply to the brain.


Energy Charge Perfusion Medium Spontaneous Electrical Activity Brain Preparation Adenylate Pool 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Josef Krieglstein
    • 1
  1. 1.Institut für Pharmakologie und ToxikologiePhilipps-UniversitätMarburgGermany

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