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Steroid Hormone Receptors in Brain and Pituitary

Topography and Possible Functions

  • Chapter
Reproduction

Part of the book series: Handbook of Behavioral Neurobiology ((HBNE,volume 7))

Abstract

That steroid hormones influence brain function and behavior has been an experimentally documented observation since the work of Berthold (1849) on the testicular control of mating and aggressive behavior in roosters. The role of gonadal steroids in the control of mating behavior is perhaps best described as a permissive action in which physical stimuli from the sexual partner actually trigger the behavior. However, the primary permissive role of gonadal steroids such as estradiol and testosterone does not appear to be that of a costimulus in that the hormone does not necessarily have to be present at the time that the behavior is elicited. This circumstance can now be better understood in the light of new information concerning a cellular mechanism of steroid hormone action that appears to be universal for all steroid target tissues, neural and nonneural. It is the purpose of this chapter to describe this cellular mechanism of steroid hormone action and to review evidence of its operation in the central nervous system and the pituitary gland in relation to the specific behavioral and neuroendocrine processes that are regulated by steroid hormones.

The work performed in this laboratory was supported by research grant NS07080 from the National Institutes of Health, and by Rockefeller Foundation grant RF70095 for research in reproductive biology.

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Authors and Affiliations

  1. The Rockefeller University, New York, New York, 10021, USA

    Victoria N. Luine & Bruce S. McEwen

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  1. Victoria N. Luine
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  2. Bruce S. McEwen
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Editors and Affiliations

  1. Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Norman Adler

  2. Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, New York, USA

    Donald Pfaff

  3. Wisconsin Regional Primate Research Center, Madison, Wisconsin, USA

    Robert W. Goy

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© 1985 Plenum Press, New York

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Luine, V.N., McEwen, B.S. (1985). Steroid Hormone Receptors in Brain and Pituitary. In: Adler, N., Pfaff, D., Goy, R.W. (eds) Reproduction. Handbook of Behavioral Neurobiology, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4832-0_14

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  • DOI: https://doi.org/10.1007/978-1-4684-4832-0_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4834-4

  • Online ISBN: 978-1-4684-4832-0

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