Abstract
In 1970, Baulieu published a paper entitled “The Action of Hormone Metabolites: A New Concept in Endocrinology.” The new concept advanced by Baulieu was that the secretions of endocrine glands may exert their biological actions only after intracellular metabolism to active agents. Specifically, Baulieu suggested that testosterone (T) maintains growth and secretion of target tissues (e.g., the prostate) by local metabolism to dihydrotestosterone (DHT) and 3α, 5α-androstanediol (abbreviated Adiol; the chemical names, trivial names, and abbreviations of most of the steroids and drugs referred to in this chapter are given in Table 1).
Unpublished research cited here was supported by grants HD-00893 to Richard E. Whalen and MH-26481 to Pauline Yahr.
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Whalen, R.E., Yahr, P., Luttge, W.G. (1985). The Role of Metabolism in Hormonal Control of Sexual Behavior. In: Adler, N., Pfaff, D., Goy, R.W. (eds) Reproduction. Handbook of Behavioral Neurobiology, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4832-0_13
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