Skip to main content

The Role of Regional Centers for Gestational Trophoblastic Disease

  • Chapter
Human Trophoblast Neoplasms

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 176))

  • 56 Accesses

Abstract

The concept of establishing regional centers for the management of patients with gestational trophoblastic disease (GTD) evolved as a direct result of the success of the program established by Dr. Roy Hertz at the National Cancer Institute. A number of individuals trained in the field of obstetrics and gynecology emerged from the clinical fellowship program at that institution who recognized that they had both an obligation and an opportunity to create in their own academic centers the type of facility which had functioned so well on a national level for over 10 years. Decentralization, as it were, would at the same time make available this new therapeutic modality to the largest number of patients and provide an adequate source of material for expanded clinical and laboratory research and teaching programs.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Goldstein, D. P., Prevention of gestational trophoblastic disease by use of actinomycin D in molar pregnancies, Obstet. Gynecol. 43: 475 (1974).

    CAS  Google Scholar 

  2. Goldstein, D. P., and Berkowitz, R.S., “Gestational Trophoblastic Neoplasms - Clinical Principles of Diagnosis and Management,” W. B. Saunders Company, Philadelphia, 1982.

    Google Scholar 

  3. Goldstein, D. P., Berkowitz, R. S., and Bernstein, M. R., Management of molar pregnancy, J. Reprod. Med. 26: 208 (1981).

    PubMed  CAS  Google Scholar 

  4. Goldstein, D. P., Berkowitz, R. S., and Cohen, S. M., The current management of molar pregnancy, Curr. Probl. Obstet. Gynecol. 3: 1 (1979).

    Google Scholar 

  5. Goldstein, D. P., Chorionic gonadotropin, Cancer 38: 453 (1976).

    Article  PubMed  CAS  Google Scholar 

  6. Berkowitz, R. S., Goldstein, D. P., Marean, A. R., and Bernstein, M. R., Oral contraceptives and postmolar trophoblastic disease, Obstet. Gynecol. 58: 474 (1981).

    CAS  Google Scholar 

  7. Goldstein, D. P., and Berkowitz, R. S., The management of gestational trophoblastic neoplasms, Curr. Probl. Obstet. Gynecol. 3: 1 (1980).

    Google Scholar 

  8. Bagshawe, K. D., Risk and prognostic factors in trophoblastic neoplasia, Cancer 38: 1373 (1976).

    Article  PubMed  CAS  Google Scholar 

  9. Berkowitz, R. S., and Goldstein, D. P., Methotrexate with citrovorum factor rescue and non-metastatic gestational trophoblastic neoplasms, Obstet. Gynecol. 54: 725 (1979).

    CAS  Google Scholar 

  10. Berkowitz, R. S., Goldstein, D. P., Jones, M. A., Marean, A. R., and Bernstein, M. R., Methotrexate with citrovorum factor rescue: reduced chemotherapy toxicity in the management of gestational trophoblastic neoplasms, Cancer 45: 423 (1980).

    Article  PubMed  CAS  Google Scholar 

  11. Berkowitz, R. S., Goldstein, D. P., and Bernstein, M. R., Methotrexate with citrovorum rescue as a primary therapy for gestational trophoblastic disease, Cancer 50: 2024 (1982).

    Article  PubMed  CAS  Google Scholar 

  12. Osathanondh, R., Goldstein, D. P., and Pastorfide, G. B., Actinomycin D as the primary agent for gestational trophoblastic disease, Cancer 36: 863 (1975).

    Article  PubMed  CAS  Google Scholar 

  13. Goldstein, D. P., The chemotherapy of gestational trophoblastic disease: principles of clinical management, J. Amer. Med. Assocn. 220: 209 (1972).

    Article  CAS  Google Scholar 

  14. Berkowitz, R. S., Goldstein, D. P., and Bernstein, M. R., Management of nonmetastatic trophoblastic tumors, J. Reprod. Med. 26: 219 (1981).

    PubMed  CAS  Google Scholar 

  15. Goldstein, D. P., and Berkowitz, R. S., Nonmetastatic and low risk metastatic gestational trophoblastic neoplasms, Seminars in Oncology 9: 191 (1982).

    PubMed  CAS  Google Scholar 

  16. Shirley, R. L., Goldstein, D. P., and Collins, J. J., Jr., The role of thoracotomy in the management of patients with chest metastases from gestational trophoblastic disease, J. Thor. Cardio. Surg. 63: 545 (1972).

    CAS  Google Scholar 

  17. Brace, K. C., The role of irradiation in the treatment of metastatic trophoblastic disease, Radiology 91: 540 (1968).

    Google Scholar 

  18. Hammond, C. B., Weed, J. C., Jr., and Currie, J. L., The role of operation in the current therapy of gestational trophoblastic disease, Amer. J. Obstet. Gynecol. 136: 844 (1980).

    CAS  Google Scholar 

  19. Pastorfide, G. B., and Goldstein, D. P., Pregnancy after hydatidiform mole, Obstet. Gynecol. 42: 67 (1973).

    CAS  Google Scholar 

  20. Goldstein, D. P., Berkowitz, R. S., and Bernstein, M. R., Reproductive performance after molar pregnancy and gestational trophoblastic tumors, Clin. Obstet. Gynecol. 27: 221 (1984).

    CAS  Google Scholar 

  21. Federschneider, J. M., Goldstein, D. P., Berkowitz, R. S., Marean, A. R., and Bernstein, M. R., Natural history of recurrent molar pregnancy, Obstet. Gynecol. 55: 457 (1980).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Plenum Press, New York

About this chapter

Cite this chapter

Goldstein, D.P., Berkowitz, R.S. (1984). The Role of Regional Centers for Gestational Trophoblastic Disease. In: Pattillo, R.A., Hussa, R.O. (eds) Human Trophoblast Neoplasms. Advances in Experimental Medicine and Biology, vol 176. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4811-5_23

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-4811-5_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4813-9

  • Online ISBN: 978-1-4684-4811-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics