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Interactions between Mg and Blood Pressure

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Book cover Phosphate and Mineral Metabolism

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 178))

Abstract

The relationship between magnesium and blood pressure has been sought, evaluated and studied in considerable depth both in the intact animal and at the level of the various organs involved. In the simplest form, three potential interactions are possible (Table 1). Although new insights have been gained regarding the acute effects of Mg loading or withdrawal on muscle cell excitability-contraction coupling, the contractile process and energy metabolism, present knowledge is still inadequate to establish the first form of interaction, viz. whether changes in Mg metabolism would produce sustained alterations in blood pressure in the intact but complex animal, endowed with all the physiologic counterregulatory and/or adaptive mechanisms. Bluntly put, the role of disturbances in Mg homeostasis, if any, has not been sufficiently defined in the pathogenesis and/or maintenance of hypertension.

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Authors and Affiliations

  1. Division of Nephrology Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan, USA

    Kai Lau & Claire Oasa

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  1. Kai Lau
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Editors and Affiliations

  1. University of Southern California, Los Angeles, California, USA

    Shaul G. Massry

  2. University of Verona, Verona, Italy

    Giuseppe Maschio

  3. University of Heidelberg, Heidelberg, Federal Republic of Germany

    Eberhard Ritz

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© 1984 Plenum Press, New York

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Lau, K., Oasa, C. (1984). Interactions between Mg and Blood Pressure. In: Massry, S.G., Maschio, G., Ritz, E. (eds) Phosphate and Mineral Metabolism. Advances in Experimental Medicine and Biology, vol 178. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4808-5_36

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  • DOI: https://doi.org/10.1007/978-1-4684-4808-5_36

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4810-8

  • Online ISBN: 978-1-4684-4808-5

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