Abstract
This chapter focuses upon results from our recent studies concerning the drug specificities and regulatory profiles of high-affinity muscarinic agonist binding site subtypes. The data are presented in conjunction with other evidence for muscarinic receptor subtypes and a significant portion of the discussion emphasizes the potential involvement of distinct receptor-effector coupling mechanisms for these subtypes. Other reviews relevant to this topic are currently available (1–4).
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Vickroy, T.W., Watson, M., Yamamura, H.I., Roeske, W.R. (1984). Differential Regulation of Putative M1/M2 Muscarinic Receptors: Implications for Different Receptor-Effector Coupling Mechanisms. In: Kito, S., Segawa, T., Kuriyama, K., Yamamura, H.I., Olsen, R.W. (eds) Neurotransmitter Receptors. Advances in Experimental Medicine and Biology, vol 175. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-4805-4_8
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