Role of Epigenetic Factors in Dietary Carcinogenesis

  • David L. Berry
  • C. Tucker Helmes
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 177)


Sixty to eighty percent of all human cancers are associated with our environment and environmental agents. The environment is a complex mixture of chemicals that originate from industrial and technological development and, most importantly, natural sources. Many industrial chemicals, pesticides, insecticides and food additives have exhibited carcinogenic properties in various animal model systems, and occupational and drug exposure has led to human cancers. However, estimates attribute the majority of human cancers associated with the environment not to intentional or accidental chemical exposure, but to the vast number of naturally occurring chemicals in our environment (Doll and Peto, 1981).


Bile Acid Mammary Tumor Tumor Incidence Epigenetic Factor Esophageal Tumor 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • David L. Berry
    • 1
  • C. Tucker Helmes
    • 2
  1. 1.WRRC, Toxicology & Biological Evaluation Research UnitUnited States Department of AgricultureBerkeleyUSA
  2. 2.Biological and Environmental Chemistry Department Life Sciences DivisionSRI InternationalMenlo ParkUSA

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