Genetic and Carcinogenic Effects of Plant Flavonoids: An Overview

  • James T. MacGregor
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 177)


Flavonoids, a diverse group of naturally occurring plant constituents which share the common structural feature of two phenyl rings linked by a three-carbon chain (Geissman and Hinreiner, 1952), are practically ubiquitous among vascular plants (Geissman, 1962), including food plants (Bate-Smith, 1954; Kühnau, 1976). The three-carbon chain may be formed into a third six-membered ring through an oxygen on one of these phenyl rings, and the naturally occurring derivatives are frequently polyphenolic. The structure and numbering of some common naturally-occurring flavonoids are illustrated in Figure 1.


Mutagenic Activity Sister Chromatid Exchange Strain TA100 Plant Flavonoid Hamster Embryo Cell 
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© Plenum Press, New York 1984

Authors and Affiliations

  • James T. MacGregor
    • 1
  1. 1.Western Regional Research CenterUnited States Department of AgricultureBerkeleyUSA

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