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Thermal Analysis on the State of Free and Bound Water in Normal and Edematous Brains

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Book cover Recent Progress in the Study and Therapy of Brain Edema

Abstract

Analysis of the state of tissue water in brain parenchyma is essential for studying the pathogenesis of brain edema. However, due to technological problems the state of water in tissue remains difficult to assess. Ambo1 attempted in 1951 to measure bound water by the cobalt chloride method applied to formalin-fixed brain. Utilizing NMR, Go and Edzes5 studied in 1975 the state of protons of fresh brain tissue and found an increase in relaxation time of edematous brain tissue compared to controls. An increase of relaxation time is considered to result from an increase of free water. However, absolute values of free and bound water have not been determined yet.

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References

  1. Ambo H: Experimental swelling of the brain and its bound water, Acta Pathol Japon 1, 63–71 (1951).

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  2. Ambo H: Klinische Bemerkungen ueber die Hirnschwellung, Auf Ergebnissen der experimentellen Untersuchungen basierend. Folia Psychiat Neurol Japon 15, 40–71 (1961).

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  3. Bering EA: Water exchange of central nervous system and cere-brospinal fluid. J Neurosurg 9, 275–287 (1952).

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  4. Furuse M, Kuchiwaki H, Gonda T, Kageyama N, Kawajiri H, Kontani J: Thermoanalytical investigation on the state of free and bound water in normal and edematous brains, J CBF & Metab 1 (supl. l) 154–155 (1981).

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  5. Go KG, Edzes HT: Water in brain edema, Observation by pulsed nuclear magnetic resonance technique, Arch Neurol 32: 462–465 (1975).

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  6. Kuntz ID, Kauzmann W: Hydration of proteins and poly-peptides. Adv Protein Chem 38: 239–345 (1974).

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Nagoya University School of Medicine, 65 Tsuruma-Cho, Showa-Ku, Nagoya 466, Japan

    Masahiro Furuse, Takami Gonda, Hiroji Kuchiwaki, Nagatoshi Hirai, Suguru Inao & Naoki Kageyama

Authors
  1. Masahiro Furuse
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  2. Takami Gonda
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  3. Hiroji Kuchiwaki
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  4. Nagatoshi Hirai
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  5. Suguru Inao
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  6. Naoki Kageyama
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Editor information

Editors and Affiliations

  1. University of Groningen, Groningen, The Netherlands

    K. G. Go

  2. Institute of Surgical Research Grosshadern Clinic H, University of Munich, Munich, Federal Republic of Germany

    A. Baethmann

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© 1984 Plenum Press, New York

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Furuse, M., Gonda, T., Kuchiwaki, H., Hirai, N., Inao, S., Kageyama, N. (1984). Thermal Analysis on the State of Free and Bound Water in Normal and Edematous Brains. In: Go, K.G., Baethmann, A. (eds) Recent Progress in the Study and Therapy of Brain Edema. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4616-6_28

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  • DOI: https://doi.org/10.1007/978-1-4684-4616-6_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4618-0

  • Online ISBN: 978-1-4684-4616-6

  • eBook Packages: Springer Book Archive

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