Abstract
Biomembranes play an extremely important role in maintaining normal energy production in the cell and in the transport of essential molecules. The individual components of the cellular membrane itself are not stable, but rather undergo continuous turnover while maintaining homeostasis. Phospholipids are an important element in these membranes and particularly in the brain where membraneous structures are numerous, they constitute a large volume. The metabolism of brain phospholipid is consequently a topic of great interest.
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References
Allen RJL: The estimation of phosphorus: Biochem J, 34: 858–865 (1940).
Bazan NG Jr: Effect of ischemia and electroconvulsive shock on free fatty acid pool in the brain. Biochim Biophys Acta, 218: 1–10 (1970).
Beyer-Mears A, Barnett A: dexamethasone preservation of motor function in phospholipase A2-induced caudate lesions. Exp Neurol 68: 240–248 (1980).
Blomstrand R, Nakayama F: Neutron activation paper Chromatographic analysis of human cerebrospinal fluid. J Neurochem 8: 230–233 (1961).
Broniszewska-Ardelt B, Dabrowiecki Z: Studies on the inhibition of brain phosphofructokinase by oleate and the determination of fatty acids in normal and hypoxic brain, J Neurochem 27: 585–587 (1976).
Chan PH, Fishman RA: Brain edema: Induction in cortical slices by polyunsaturated fatty acids. Science, 201: 358–360 (1978).
Cooper MF, Webster GR: On the phospholipase A2 activity of human cerebral cortex. J Neurochem, 19: 333–340 (1972).
Corbin DR, Sun GY: Characterization of the enzymic transfer of arachidnoyl groups to 1-acylphosphoglycerides in mouse syn-aptosome fraction. J Neurochem 30: 77–82 (1978).
Gullis RJ, Rowe CE: The stimulation of the phospholipase A2-acylation system of synaptic membranes of brain by cyclic nucleotides. Biochem J, 148: 567–581 (1975).
Gullis RJ, Rowe CE: The stimulation by transmitter substances and putative transmitter substances of the net activity of phospholipase A2 of synaptic membranes of cortex of guinea-pig brain. Biochem J, 148: 197–208 (1975).
Gullis RJ, Rowe CE: The stimulation by synaptic transmitters of the incorporation of oleate into the phospholipid of synaptic membranes. Biochem J, 148: 557–565 (1975).
Inoh S, Yoshida S, Sano K: Brain free fatty acids and phospho-lipids in experimental cerebral ischemia-role of post-ischemic lipid peroxidation. No To Shinkei, 32: 829–838 (1980) (Eng Abstr) (Jpn).
Kuwashima J, Fujitani B, Nakamura K, Kadokawa T, Yoshida K, Shimizu M: Biochemical changes in unilateral brain injury in the rat: A possible role of free fatty acid accumulation. Brain Res, 110: 547–557 (1976).
Lands WEM: Metabolism of glycerolipid II. The enzymatic acyla-tion of lysolecithin. J Biol Chem, 235: 2233–2237 (1960).
Lunt GG, Rowe CE: The production of unesterified fatty acid in brain. Biochim Biophys Acta, 152: 681–693 (1968).
Papadopulos NM, Cevallos W, Hess WC: Determination of phospho-lipids in spinal fluid and brain. Arch Neurol, 3: 677–682 (1960).
Sun GY, Su KL, Der OM, Tang W: Enzymic regulation of arachido-nate metabolism in brain membraine phosphoglycerides. Lipid, 14: 229–235, (1978).
Suzuki J, Yoshimoto T, Tanaka S, Sakamoto T: Production of various models of cerebral infarction in the dogs by means of occlusion of intracranial trunk arteries. Stroke, 11: 337–341 (1980).
Thompson RHS, Niemiro R, Webster GR: The identification of lysolecithin in lipid extracts of brain. Biochim Biophys Acta, 43: 142–144 (1960).
Webster GR, Thompson RHS: Observations of the presence of lysolecithin in nervous tissues. Biochim Biophys Acta, 63: 38–45 (1962).
Webster GR, Alpern RJ: Studies of the acylation of lysolecithin by rat brain. Biochem J, 90: 35–42 (1964).
Webster GR, Thompson RHS: Accumulation of lysolecithin in rat brain on incubation in vitro Nature, 206: 296–297 (1965).
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© 1984 Plenum Press, New York
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Hirashima, Y., Koshu, K., Kamiyama, K., Nishijima, M., Endo, S., Takaku, A. (1984). The Activities of Phospholipase Al, A2, Lysophospholipase and Acyl CoA: Lysophospholipid Acyltransferase in Ischemic Dog Brain. In: Go, K.G., Baethmann, A. (eds) Recent Progress in the Study and Therapy of Brain Edema. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4616-6_20
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DOI: https://doi.org/10.1007/978-1-4684-4616-6_20
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