Abstract
The excessive transfer of water from blood to brain tissue during the development of edema is dependent upon a series of interrelated circulatory, vascular and tissue factors. The circulatory factors have long since been the subject of research19,9,10. The most important role is certainly played by the intravascular pressure which is forcing the water across the vascular walls into the cerebral tissue9,10,8,12,4,l. The cerebral blood pressure (i.e. predominantly the pressure in the brain capillaries) is, on the one hand, dependent upon the systemic arterial and venous pressures, and, on the other hand, on the cerebral arterial resistance.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Auer L: The role of cerebral perfusion pressure as origin of brain edema in acute arterial hypertension. Eur Neurol 15: 153–156 (1977).
Bering EA: Water exchange of central nervous system and cere-brospinal fluid. J Neurosurg 9: 275–287 (1952).
Blinkow SM, Gleser II: Das Zentralnervensystem in Zahlen und Tabellen. Jena: Gustav Fischer Verlag (1968).
Gannushkina IV, Shafranova VP: The differences of arterial autoregulation in gray and white matter in acute hypertension. In: Blood flow and metabolism in the brain, Harper M, Jennett B, Miller J et al (Eds), Edinburgh-London-New York: Churchill Livingstone, 5.31–5.35 (1977).
Greenberg JH, Alavi A, Reivich A, Kuhl D, Uzzell B: Local cerebral blood volume response to carbon dioxide in man Circ Res, 43: 324–331 (1978).
Haddy FJ, Scott JB, Grega GJ: Peripherial circulation: fluid transfer across the microvascular membrane. In: International Review of Physiology, volume 9, Cardiovascular Physiology II, Guyton AC, Cowley AW (Eds), Baltimore-London-Tokyo: University Park Press, 63–109 (1976).
Ito U, Ohno K, Nakamura R, Suganuma F, Inaba Y: Brain edema during ischemia after restoration of blood flow. Stroke 10: 542–547 (1979).
Klatzo I, Wiśniewski H, Steinwall O, Streicher E: Dynamics of cold injury edema. In: Brain edema, Klatzo I, Seitelberger F (Eds) Springer New York, 554–563 (1967).
Mchedlishvili GI, Akhobadze VA: The cerebral arterial system in brain injury and during traumatic edema. Physiol Bohemoslove-nica 10: 8–14 (1961).
Mchedlishvili GI, Akhobadze VA: The functional state of the capillary and venous systems of the brain in cerebral traumatic edema. Physiol Bohemoslovenica 10: 15–20 (1961).
Mchedlishvili GI: A chest-head preparation for investigation of the cerebral circulation. Bull exper Biol Med (Moscow) 53: 123–125 (1962).
Mchedlishvili GI, Kapuściński A, Nikolaishvili L: Mechanisms of postischemic brain edema: contribution of circulatory factors. Stroke 7: 410–416 (1976).
Mchedlishvili G, Nikolaishvili L, Itkis M: Pathophysiological mechanisms of brain edema development: role of tissue factors. Stroke 10: 52–57 (1979).
Mchedlishvili GI, Mossakowski M, Itkis ML: Changes in mechanical properties of brain tissue as factor of brain edema development. Neuropat Pol 18: 543–554 (1980).
Mchedlishvili GI, Sikharulidze NV, Itkis ML, Januszewski S: Cerebral venous pressure, its relation to systemic venous pressure and brain edema development. Bull exper Biol and Med (Moscow) 89: 14–16 (1980).
Mchedlishvili GI, Itkis ML, Sikharulidze NV: Mechanical properties of the brain during development of postischemic edema. Voprosy Neirokhirurgii (Moscow), no. 6 (in press) (1981).
Mchedlishvili GI: The brain pre-edema. J Neurosurg 54: 848 (1981).
Mchedlishvili GI, Lazriev L, Tsitsishvili A, Sikharulidze N: Ischemic changes in brain interstitial space volume. IRCS Med Sci 9: 399–400 (1981).
Meyer JS, Denny-Brown D: Studies of cerebral circulation in brain injury. 1. Validity of combined local cerebral electro-polarography, thermometry and steady potentials as an indicator of local circulatory and functional changes. EEG Clin Neuro-physiol 7: 511–528 (1955).
Penn RD, Walser R, Ackerman L: Cerebral blood volume in man. Computer analysis of a computerized brain scan. J Amer Med Ass 234: 1154–1155 (1975).
Phelps ME, Crubb RL, Ter-Pogossian MM: In vivo regional cerebral blood volume by X-ray fluorescence: validation of method. J appl Physiol 35: 741–747 (1973).
Raichle ME, Eichling JO, Straatmann MJ, Welch MJ, Larson KB, Ter-Pogossian MM: Blood-brain barrier permeability of 11C-labeled alcohols and 150-labeled water. Am J Physiol 230: 543–552 (1976).
Sklar FH, Bruke EF, Langfitt TW: Cerebral blood volume obtained with 51Cr-labeled red blood cells and RISA. J appl Physiol 24: 79–82 (1968).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Plenum Press, New York
About this chapter
Cite this chapter
Mchedlishvili, G., Mossakowski, M., Itkis, M., Sikharulidze, N., Januszewski, S. (1984). Cerebral Blood Volume Changes During the Development of Brain Edema. In: Go, K.G., Baethmann, A. (eds) Recent Progress in the Study and Therapy of Brain Edema. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4616-6_13
Download citation
DOI: https://doi.org/10.1007/978-1-4684-4616-6_13
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-4618-0
Online ISBN: 978-1-4684-4616-6
eBook Packages: Springer Book Archive