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Recognition Sites for Antidepressant Drugs

  • Chapter
Handbook of Neurochemistry

Abstract

It has been almost two decades since the discovery that tricyclic antidepressants and monoamine oxidase (MAO) inhibitors were clinically effective in the treatment of depression. In spite of intensive investigations, neither the mo lecular mechanisms whereby antidepressants operate nor the etiology of this disease is well understood. The knowledge that reserpine, which depletes monoamine stores,1,2 can induce a depressed mood 3 has stimulated speculation on a causal relationship between a defect in monoaminergic transmission and endogenous depression.

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References

  1. Brodie, B. B., Pletsher, A., and Shore, P. A., 1956, Science 123:992–994.

    PubMed  CAS  Google Scholar 

  2. Holzbauer, M., and Vogt, M., 1956, J. Neurochem. 1:8–11.

    PubMed  CAS  Google Scholar 

  3. Brodie, B. B., and Shore, P. A., 1957, Ann. N.Y., Acad. Sci. 66:631–638.

    CAS  Google Scholar 

  4. Carlsson, A., Corrodi, H., Fuxe, K., and Hokfelt, T., 1969, Eur. J. Pharmacol. 5:357–366.

    PubMed  CAS  Google Scholar 

  5. Carlsson, A., Johanson, J., Lindquist, M., and Fuxe, K., 1959, Brain Res. 12:456–460.

    Google Scholar 

  6. Glowinski, J., and Axelord, J., 1964, Nature 204:1318–1319.

    PubMed  CAS  Google Scholar 

  7. Ross, S. B., and Renyl, A. L., 1967, Eur. J. Pharmacol. 2:181–186.

    PubMed  CAS  Google Scholar 

  8. Thomas, P. C., and Jones, P. B., 1977, J. Pharm. Pharmacol. 29:562–563.

    PubMed  CAS  Google Scholar 

  9. Hamberger, B., and Tuck, J. R., 1973, Eur. J. Clin. Pharmacol. 5:229–235.

    CAS  Google Scholar 

  10. Bunney, W. E., and Davis, J. M., 1965, Arch. Gen. Psychiatry 13:483–494.

    PubMed  CAS  Google Scholar 

  11. Schildkraut, J. J., 1965, Am. J. Psychiatry 122:509–522.

    PubMed  CAS  Google Scholar 

  12. Post, R. M., and Goodwin, F. K., and 1978, Handbook of Psychopharmacology ,Volume 13 (L. L. Iversen, Iversen, S. D., and S. H. Snyder, eds.), Raven Press, New York, pp. 1235–1247.

    Google Scholar 

  13. Van Praag, H. M., 1978, Acta Psychiatr. Scand. 57:389–404.

    PubMed  Google Scholar 

  14. Garver, D. L., and Davis, J. M., 1979, Life Sci. 24:383–391.

    PubMed  CAS  Google Scholar 

  15. Kostowski, W., 1981, Science 6:314–317.

    Google Scholar 

  16. Murphy, D. L., Campbell, I., and Costa, J. L., 1978, Psychopharmacology (M. A. Lipton, A. DiMascio, and K. K. Killam, eds.), Raven Press, New York, pp. 1235–1247.

    Google Scholar 

  17. Leonard, B. E., 1974, Psychopharmacologia 36:221–236.

    PubMed  CAS  Google Scholar 

  18. Goodlet, I., Mireylees, S. E., and Sugrue, M. F., 1977, Br. J. Pharmacol. 61:307–313.

    PubMed  CAS  Google Scholar 

  19. Rosloff, B. N., and Davis, J. M., 1974, Psychopharmacologia 40:53–64.

    PubMed  CAS  Google Scholar 

  20. Ferris, R. M., Maxwell, R. A., Cooper, R. A., and Soroko, F. E., 1982, Advances in Bio chemical Psychopharmacology ,Volume 31 (E. Costa and G. Racagni, eds.), Raven Press, New York, pp. 277–286.

    Google Scholar 

  21. Hertting, G., Axelrod, J., and Whitby, L., 1961, J. Pharmacol. Exp. Ther. 134:146–153.

    CAS  Google Scholar 

  22. Nielsen, M., 1975, J. Pharmacol. 27:206–208.

    CAS  Google Scholar 

  23. Roffman, M., Kling, M. A., Cassens, G., Orsulak, P. J., Reigle, T. G., and Schildkraut, J. J., 1977, Psychopharmacol. Commun. 1:195–206.

    CAS  Google Scholar 

  24. Bareggi, S. R., Markey, K., and Genovese, E., 1978, Eur. J. Pharmacol. 50:301–308.

    PubMed  CAS  Google Scholar 

  25. Tang, S. W., Helmeste, D. M., and Stancer, H. C., 1978, Naunyn Schmiedebergs Arch. Pharmacol. 305:207–211.

    PubMed  CAS  Google Scholar 

  26. Neff, N. H., and Costa, E., 1967, Antidepressant Drugs (S. Garattini and M. N. H. Dukes, eds.), Excerpta Medica, Amsterdam, pp. 28–34.

    Google Scholar 

  27. Schildkraut, J. J., Roffman, M., Orsulak, P. J., Schatzberg, A. F., Kling, M. A., and Reigle, T. G., 1976, Pharmakopsychiatrie 9:193–202.

    CAS  Google Scholar 

  28. Sugrue, M. F., 1980, Life Sci. 26:423–429.

    PubMed  CAS  Google Scholar 

  29. Schildkraut, J. J., Winokur, A., Draskoczy, P. R., and Hensle, J. H., 1971, Am. J. Psychiatry 127:72–79.

    Google Scholar 

  30. Van Wijk, M., Meisch, J. J., and Korf, J., 1977, Psychopharmacology 55:217–223.

    PubMed  Google Scholar 

  31. Corrodi, H., and Fuxe, K., 1969, Pharmacology 7:56–59.

    CAS  Google Scholar 

  32. Meek, J. L., and Werdinius, B., 1970, J. Pharm. Pharmacol. 22:141–143.

    PubMed  CAS  Google Scholar 

  33. Goodlet, I., and Sugrue, M. F., 1974, Eur. J. Pharmacol. 29:241–248.

    PubMed  CAS  Google Scholar 

  34. Marcro, E. J., and Meek, J. L., 1979, Naunyn Schmiedebergs Arch. Pharmacol. 306:75–79.

    Google Scholar 

  35. Nielsen, M., and Braestrup, C., 1977, Naunyn Schmiedbergs Arch. Pharmacol. 300:87–92.

    CAS  Google Scholar 

  36. Raiteri, M., Angelini, F., and Bertollini, A., 1976, J. Pharm. Pharmacol. 28:483–488.

    PubMed  CAS  Google Scholar 

  37. Kafoe, W. F., DeRidder, J. J., and Leonard, B. E., 1976, Biochem. Pharmacol. 25:2455–2460.

    PubMed  CAS  Google Scholar 

  38. Van Riezen, H., 1972, Arch. Int. Pharmacodyn. 198:256–269.

    PubMed  Google Scholar 

  39. Maj, J., Sowinska, H., Baran, L., Gancarczyk, L., and Rawlow, A., 1978, Psychopharmacology 59:79–84.

    PubMed  CAS  Google Scholar 

  40. Rosloff, B. N., and Davis, J. M., 1978, Psychopharmacology 56:335–341.

    PubMed  CAS  Google Scholar 

  41. Sherman, A., 1979, Psychopharmacol. Commun. 3:1–5.

    CAS  Google Scholar 

  42. Sanghvi, I., and Gershon, S., 1975, Biochem. Pharmacol. 24:2103–2104.

    PubMed  CAS  Google Scholar 

  43. Ross, S. B., Ogren, S. O., and Renyi, A. L., 1976, Acta Pharmacol. Toxicol. 39:152–166.

    CAS  Google Scholar 

  44. Fuller, R. W., Perry, K. W., and Molloy, B. B., 1975, J. Pharmacol. Exp. Ther. 193:796–803.

    CAS  Google Scholar 

  45. Wong, D. T., Bymaster, F. P., Horng, J. S., and Malloy, B. B., 1975, J. Pharmacol. Exp. Ther. 193:804–811.

    PubMed  CAS  Google Scholar 

  46. Fuxe, K., Ogren, S.-O., and Agnati, L. F., 1979, Neurosci. Lett. 13:307–312.

    PubMed  CAS  Google Scholar 

  47. Hwang, E. C., and Van Woert, M. H., 1980, Psychopharmacol. Commun. 4:161–167.

    CAS  Google Scholar 

  48. Langer, S. Z., 1974, Biochem. Pharmacol. 23:1793–1800.

    PubMed  CAS  Google Scholar 

  49. Berthelsen, S., and Pettinger, W. A., 1977, Life Sci. 21:595–606.

    PubMed  CAS  Google Scholar 

  50. Starke, K., and Langer, S. Z., 1979, Presynaptic Receptors (S. Z. Langer, K. Starke, and M. L. Dubocovich, eds.), Pergamon Press, Oxford, pp. 1–3.

    Google Scholar 

  51. U’Prichard, D. C., Bechtel, W. D., Rouot, B. M., and Snyder, S. H., 1979, Mol. Pharmacol. 16:47–60.

    PubMed  Google Scholar 

  52. Langer, S. Z., 1977, Br. J. Pharmacol. 60:481–497.

    PubMed  CAS  Google Scholar 

  53. Starke, K., Taube, H. D., and Borowski, E., 1977, Biochem. Pharmacol. 26:259–268.

    PubMed  CAS  Google Scholar 

  54. Westfall, T. C., 1977, Physiol. Rev. 57:659–728.

    PubMed  CAS  Google Scholar 

  55. Anden, N.-E., Grabowska, M., and Strombom, U., 1976, Naunyn Schmiedebergs Arch. Phar macol. 292:43–52.

    CAS  Google Scholar 

  56. Delini-Stula, A., Baumann, P., and Buch, O., 1979, Naunyn Schmiedebergs Arch. Pharmacol. 307:115–122.

    PubMed  CAS  Google Scholar 

  57. Crews, F. T., and Smith, C. B., 1978, Science 202:322–324.

    PubMed  CAS  Google Scholar 

  58. McMillen, B. A., Warnack, W., German, D. C., and Shore, P. A., 1980, Eur. J. Pharmacol. 61:239–246.

    PubMed  CAS  Google Scholar 

  59. Sugrue, M. F., 1981, Life Sci. 208:377–384.

    Google Scholar 

  60. Sugrue, M. F., 1981, Pharmacol. Ther. 13:219–249.

    PubMed  CAS  Google Scholar 

  61. Johnson, R. W., Reisine, T., Spotnitz, S., Wiech, N., Ursillo, R., and Yamamura, H. I., 1980, Eur. J. Pharmacol. 67:123–127.

    PubMed  CAS  Google Scholar 

  62. Smith, C. B., Garcia-Sevilla, J., and Hollingsworth, P. J., 1981, Brain Res. 210:413–418.

    PubMed  CAS  Google Scholar 

  63. Tang, S. W., and Seeman, P., 1980, Naunyn Schmiedebergs Arch. Pharmacol. 311:255–261.

    PubMed  CAS  Google Scholar 

  64. Maggi, A., U’Prichard, D. C., and Enna, S. J., 1980, Eur. J. Pharmacol. 61:91–98.

    PubMed  CAS  Google Scholar 

  65. Fludder, J. M., and Leonard, B. E., 1979, Psychopharmacology 64:329–332.

    PubMed  CAS  Google Scholar 

  66. Sugrue, M. F., 1980, Eur. J. Pharmacol. 68:377–380.

    PubMed  CAS  Google Scholar 

  67. Tang, S. W., Helmeste, D. M., and Stancer, H. C., 1979, Can. J. Physiol. Pharmacol. 57:435–437.

    PubMed  CAS  Google Scholar 

  68. Banerjee, S. P., Kung, L. S., Riggi, S. J., and Chanda, S. K., 1977, Nature 268:455–456.

    PubMed  CAS  Google Scholar 

  69. Sarai, K., Frazer, A., Brunswick, D., and Mendels, J., 1978, Biochem. Pharmacol. 27:2179–2181.

    PubMed  CAS  Google Scholar 

  70. Wolfe, B. B., Harden, T. K., Sporn, J. R., and Molinoff, P. B., 1978, J. Pharmacol. Exp. Ther. 207:446–457.

    PubMed  CAS  Google Scholar 

  71. Bergstrom, D. A., and Kellar, K. J., 1979, J. Pharmacol. Exp. Ther. 209:256–261.

    PubMed  CAS  Google Scholar 

  72. Dibner, M. D., and Molinoff, P. B., 1979, J. Pharmacol. Exp. Ther. 210:433–439.

    PubMed  CAS  Google Scholar 

  73. Peroutka, S. J., and Snyder, S. H., 1980, Science 210:88–90.

    PubMed  CAS  Google Scholar 

  74. Sellinger-Barnette, M. M., Mendels, J., and Frazer, A., 1980, Neuropharmacology 19:447–454.

    PubMed  CAS  Google Scholar 

  75. Kinner, W. J., Chuang, D. M., and Costa, E., 1979, Eur. J. Pharmacol. 67:289–294.

    Google Scholar 

  76. Rosenblatt, J. E., Pert, C. B., Tallman, J. F., Pert, A., and Bunney, W. E., Jr., 1979, Brain Res. 160:186–191.

    PubMed  CAS  Google Scholar 

  77. Clement-Jewery, S., 1978, Neuropharmacology 17:779–781.

    Google Scholar 

  78. Minneman, K. P., and Molinoff, P. B., 1980, Biochem. Pharmacol. 29:1317–1323.

    PubMed  CAS  Google Scholar 

  79. Minneman, K. P., Dibner, M. D., Wolfe, B. B., and Molinoff, P. B., 1979, Science 204:866–868.

    PubMed  CAS  Google Scholar 

  80. Weiss, B., Heydorn, W., and Frazer, A., 1982, Advances in Biochemical Psychopharmacology ,Volume 31, Typical and Atypical Antidepressants (E. Costa and G. Racagni, eds.), Raven Press, New York, pp. 37–54.

    Google Scholar 

  81. Chuang, D. M., and Costa, E., 1979, Proc. Natl. Acad. Sci. U.S.A. 76:3024–3028.

    PubMed  CAS  Google Scholar 

  82. Chuang, D. M., Kinnier, W. J., Farber, L., and Costa, F., 1980, Mol. Pharmacol. 18:348–355.

    PubMed  CAS  Google Scholar 

  83. Chuang, D. M., 1981, J. Biol. Chem. 256:8291–8293.

    PubMed  CAS  Google Scholar 

  84. Chuang, D. M., 1982, Biochem. Biophys. Res. Commun. 105:1466–1472.

    PubMed  CAS  Google Scholar 

  85. Bergstrom, D. A., and Kellar, K. J., 1979, Nature 278:464–466.

    PubMed  CAS  Google Scholar 

  86. Gillespie, D. D., Manier, D. H., and Sulser, F., 1979, psychopharmacol. Commun. 3:191–195.

    CAS  Google Scholar 

  87. Pandey, G. N., Heinze, W. J., Brown, B. D., and Davis, J. M., 1979, Nature 280:234–235.

    PubMed  CAS  Google Scholar 

  88. Schultz, J. E., Siggins, G. R., Shocker, F. W., Turck, M., and Bloom, F. E., 1981, J. Phar macol. Exp. Ther. 216:28–38.

    CAS  Google Scholar 

  89. Sulser, F., 1982, Advances in Biochemical Psychopharmacology ,Volume 31, Typical and Atypical Antidepressants (E. Costa and G. Racagni, eds.), Raven Press, New York, pp. 1–20.

    Google Scholar 

  90. Sulser, F., 1981, Towards Understanding Receptors (J. W. Lamble, ed.), Elsevier/North-Holland, Amsterdam, pp. 99–104.

    Google Scholar 

  91. Paul, S. M., and Crews, F. T., 1980, Eur. J. Pharmacol. 62:349–350.

    PubMed  CAS  Google Scholar 

  92. Sethy, V. H., and Harris, D. W., 1981, Eur. J. Pharmacol. 75:53–56.

    PubMed  CAS  Google Scholar 

  93. Vetulani, J., and Sulser, F., 1975, Nature 257:495–496.

    PubMed  CAS  Google Scholar 

  94. Vetulani, J., Stawarz, R. J., Dingell, J. V., and Sulser, F., 1976, Naunyn Schmiedebergs Arch. Pharmacol. 293:109–114.

    PubMed  CAS  Google Scholar 

  95. Mishra, R., Janowsky, A., and Sulser, F., 1980, Neuropharmacology 19:983–987.

    PubMed  CAS  Google Scholar 

  96. Mishra, R., Janowsky, A., and Sulser, F., 1979, Eur. J. Pharmacol. 60:379–382.

    PubMed  CAS  Google Scholar 

  97. Schweitzer, J. W., Schwartz, R., and Friedhoff, A. J., 1979, J. Neurochem. 33:377–379.

    PubMed  CAS  Google Scholar 

  98. Janowsky, A., Steranka, L. R., Gillespie, D. D., and Sulser, F., 1982, J. Neurochem. 39:290–292.

    PubMed  CAS  Google Scholar 

  99. Rehavi, M., Ramot, O., Yavetz, B., and Sokolovsky, M., 1980, Brain Res. 294:443–453.

    Google Scholar 

  100. U’Prichard, D. C., Greenberg, D. A., Sheehan, P. P., and Snyder, S. H., 1978, Science 199:197–198.

    PubMed  Google Scholar 

  101. Rehavi, M., Maayani, S., and Sokolovsky, M., 1977, Biochem. Pharmacol. 26:1559–1567.

    PubMed  CAS  Google Scholar 

  102. Reisine, T., U’Prichard, D., Wiech, N., Ursillo, R., and Yamamura, H., 1980, Brain Res. 188:587–592.

    PubMed  CAS  Google Scholar 

  103. Smith, C. B., Garcia-Sevilla, J. A., and Hollingsworth, P. J., 1981, Brain Res. 210:413–418.

    PubMed  CAS  Google Scholar 

  104. Enjalbert, A., Bourgoin, S., Hamon, M., Adrien, J., and Bockaert, J., 1978, Mol. Pharmacol. 14:2–10.

    PubMed  CAS  Google Scholar 

  105. Fillion, G., Rousselle, J. C., Beaudoin, D., Pradelles, P., Goiny, M., Dray, F., and Jacob, J., 1979, Life Sci. 24:1815–1822.

    Google Scholar 

  106. Barbaccia, M. L., Brunello, N., Chuang, D. M., and Costa, E., 1983,7. Neurochem. 40:1671–1679.

    CAS  Google Scholar 

  107. Savage, D. D., Frazer, A., and Mendels, J., 1979, Eur. J. Pharmacol. 58:87–88.

    PubMed  CAS  Google Scholar 

  108. Savage, D. D., Mendels, J., and Frazer, A., 1980, J. Pharmacol. Exp. Ther. 212:259–263.

    PubMed  CAS  Google Scholar 

  109. Peroutka, S. J., and Snyder, S. H., 1979, Mol. Pharmacol. 16:687–689.

    PubMed  CAS  Google Scholar 

  110. Peroutka, S. J., and Snyder, S. H., 1981, J. Pharmacol. Exp. Ther. 216:142–148.

    PubMed  CAS  Google Scholar 

  111. Leysen, J. E., Niemegeers, C. J. E., Van Neuten, J. M., and Laduron, P. M., 1982, Mol. Pharmacol. 21:301–314.

    PubMed  CAS  Google Scholar 

  112. Barbaccia, M. L., Gandolfi, O., Chuang, D. M., and Costa, E., 1983, Neuropharmacology 22:123–126.

    PubMed  CAS  Google Scholar 

  113. Brunello, N., Chuang, D. M., and Costa, E., 1982, Science 215:1112–1115.

    PubMed  CAS  Google Scholar 

  114. Brunello, N., Chuang, D. M., and Costa, E., 1982, Advances in the Bioscience: New Vistas in Depression ,Volume 40 (S. Z. Langer, R. Takahashi, and M. Briley eds.), Pergamon Press, Oxford, New York, pp. 141–145.

    Google Scholar 

  115. Segawa, T., Mizuta, T., and Nomura, Y., 1979, Eur. J. Pharmacol. 58:75–83.

    PubMed  CAS  Google Scholar 

  116. Wirz-Justice, A., Krauchi, K., Lichsteiner, M., and Feer, H., 1978, Life Sci. 23:1249–1254.

    PubMed  CAS  Google Scholar 

  117. Peroutka, S. J., and Snyder, S. H., 1980, J. Pharmacol. Exp. Ther. 215:582–587.

    PubMed  CAS  Google Scholar 

  118. Briley, M., Raisman, R., Arbilla, S., Casadamont, M., and Langer, S. Z., 1982, Eur. J. Pharmacol. 81:309–314.

    PubMed  CAS  Google Scholar 

  119. Zsilla, G., Barbaccia, M. L., Gandolfi, O., Knoll, J., and Costa, E., 1983, Eur. J. Pharmacol. 89:111–117.

    PubMed  CAS  Google Scholar 

  120. Maggi, A., and Enna, S. J., 1980, J. Neurochem. 34:888–892.

    PubMed  CAS  Google Scholar 

  121. Treiser, S., and Kellar, K. J., 1979, Eur. J. Pharmacol. 64:183–185.

    Google Scholar 

  122. Kellar, K. J., Cascio, C. S., Butler, J. A., and Kurtzke, R. H., 1981, Eur. J. Pharmacol. 69:515–518.

    PubMed  CAS  Google Scholar 

  123. Borowski, E., Starke, K., Ehrl, H., and Endo, T., 1977, Neuroscience 2:285–296.

    PubMed  CAS  Google Scholar 

  124. Doxey, J. C., Everitt, J., and Metcalf, G., 1978, Eur. J. Pharmacol. 51:1–10.

    PubMed  CAS  Google Scholar 

  125. Cavero, I., Gomeni, R., LeFevre-Borg, F., and Roach, A. G., 1980, Br. J. Pharmacol. 68:321–332.

    PubMed  CAS  Google Scholar 

  126. Clineschmidt, B. V., Flataker, L. M., Faison, E., and Holmes, R., 1979, Arch. Int. Phar-macodyn. Ther. 242:59–76.

    CAS  Google Scholar 

  127. Hall, H., and Ogren, S. O., 1981, Eur. J. Pharmacol. 70:393–407.

    PubMed  CAS  Google Scholar 

  128. Black, J. W., Duncan, W. A. M., Durant, G. J., Ganellin, C. R., and Parson, E. M., 1972, Nature 236:385–390.

    PubMed  CAS  Google Scholar 

  129. Tran, V. T., Lebovitz, R., Toll, L., and Snyder, S. H., 1981, Eur. J. Pharmacol. 70:501–509.

    PubMed  CAS  Google Scholar 

  130. Taylor, J. E., and Richelson, E., 1982, Eur. J. Pharmacol. 78:279–285.

    PubMed  CAS  Google Scholar 

  131. Figge, J., Leonard, P., and Richelson, E., 1979, Eur. J. Pharmacol. 58:479–483.

    PubMed  CAS  Google Scholar 

  132. Richelson, E., 1978, Nature ,274:176–177.

    PubMed  CAS  Google Scholar 

  133. Barbaccia, M. L., Brunello, N., Chuang, D. M., and Costa, E., 1983, Neuropharmacology 22:373–383.

    PubMed  CAS  Google Scholar 

  134. Kanof, P. D., and Greengard, P., 1978, Nature 272:329–333.

    PubMed  CAS  Google Scholar 

  135. Green, J. P., and Maayani, S., 1977, Nature 269:165–166.

    Google Scholar 

  136. Hollister, L. E., 1978, N. Engl. J. Med. 299:1106–1109, 1168–1172.

    PubMed  CAS  Google Scholar 

  137. Bloom, F., Segal, D., Ling, N., and Guillemin, R., 1976, Science 194:630–632.

    PubMed  CAS  Google Scholar 

  138. Biegon, A., and Samuel, D., 1980, Biochem. Pharmacol. 29:460–462.

    PubMed  CAS  Google Scholar 

  139. Costa, E., 1981, Towards Understanding Receptors (J. W. Lamble, ed.), Elsevier/North-Holland, Amsterdam, pp. 176–183.

    Google Scholar 

  140. Squires, R. F., and Braestrup, C., 1977 Nature 266:732–734.

    PubMed  CAS  Google Scholar 

  141. Mohler, H., and Okada, T., 1977, Life Sci. 20:2101–2110.

    PubMed  CAS  Google Scholar 

  142. Massoti, M., Guidotti, A., and Costa, E., 1981, GABA and Benzodiazepine Receptors (E. Costa, G. DiChiara, and G. L. Gressa, eds.), Raven Press, New York, pp. 19–26.

    Google Scholar 

  143. Ebstein, B., Guidotti, A., and Costa, E., 1982, Problems in GABA Research from Brain to Bacteria (Y. Okada and E. Roberts, eds.), Excerpta Medica, Amsterdam, pp. 348–354.

    Google Scholar 

  144. Raisman, R., Briley, M., and Langer, S. Z., 1979, Eur. J. Pharmacol. 54:307–308.

    PubMed  CAS  Google Scholar 

  145. Raisman, R., Briley, M., and Langer, S. Z., 1979, Nature 281:148–150.

    PubMed  CAS  Google Scholar 

  146. Rehavi, M., Paul, S. M., Skolnick, P., and Goodwin, F. K., 1980, Life Sci. 26:2273–2279.

    PubMed  CAS  Google Scholar 

  147. Dumbrille-Ross, A., Tang, S. W., and Coscina, D. V., 1981, Life Sci. 29:2049–2058.

    PubMed  CAS  Google Scholar 

  148. Hirdina, P. D., Elson-Hartman, K., Roberts, D. C. S., and Rappas, B. A., 1981, Eur. J. Pharmacol. 73:375–376.

    Google Scholar 

  149. Briley, M. S., Fillion, G., Beaudoin, D., Fillion, M.-P., and Langer, S. Z., 1980, Eur. J. Pharmacol. 64:191–194.

    PubMed  CAS  Google Scholar 

  150. Briley, M. S., Raisman, R., Sechter, D., Zarifian, E., and Langer, S. Z., 1980, Neurophar macology 19:1209–1210.

    CAS  Google Scholar 

  151. Briley, M. S., and Langer, S. Z., 1981, Eur. J. Pharmacol. 72:377–380.

    PubMed  CAS  Google Scholar 

  152. Palkovits, M., Raisman, R., Briley, M., and Langer, S. Z., 1981, Brain Res. 210:493–498.

    PubMed  CAS  Google Scholar 

  153. Kinnier, W. J., Chuang, D. M., Gwynn, G., and Costa, E., 1981, Neuropharmacology 20:411– 419.

    PubMed  CAS  Google Scholar 

  154. Chuang, D. M., Brunello, N., Kinnier, W. J., and Costa, E., 1982, Advances in the Biosciences: New Vistas in Depression ,Volume 40 (S. Z. Langer, R. Takahashi, and M. Briley, eds.), Pergamon Press, Oxford, New York, pp. 133–139.

    Google Scholar 

  155. Briley, M. S., Raisman, R., and Langer, S. Z., 1979, Eur. J. Pharmacol. 58:347–348.

    PubMed  CAS  Google Scholar 

  156. Paul, S. M., Rehavi, M., Skolnick, P., and Goodwin, F. K., 1980, Life Sci. 26:953–959.

    PubMed  CAS  Google Scholar 

  157. Wennogle, L. P., Beer, B., and Meyerson, L. R., 1981, Pharmacol. Biochem. Behav. 15:975–982.

    PubMed  CAS  Google Scholar 

  158. Sette, M., Raisman, R., Briley, M., and Langer, S. Z., 1981, J. Neurochem. 37:40–42.

    PubMed  CAS  Google Scholar 

  159. Paul, S. M., Rehavi, M., Rice, K. C., Ittah, Y., and Skolnick, P., 1981, Life Sci. 28:2753–2760.

    PubMed  CAS  Google Scholar 

  160. Langer, S. Z., Morat, C., Raisman, R., Dubocovich, M. L., and Briley, M., 1980, Science 210:1133–1135.

    PubMed  CAS  Google Scholar 

  161. Rehavi, M., Ittah, Y., Rice, K. C., Skolnick, P., Goodwin, F. K., and Paul, S. M., 1981, Biochem. Biophys. Res. Commun. 99:954–959.

    PubMed  CAS  Google Scholar 

  162. Ahtee, L., Briley, M., Raisman, R., Lebrec, D., and Langer, S. Z., 1982, Life Sci. 29:2323–2329.

    Google Scholar 

  163. Brunello, N., Chuang, D. M., and Costa, E., 1982, Advances in Biochemical Psychopharmacology: Volume 31, Typical and Atypical Antidepressants (E. Costa and G. Racagni, eds.), Raven Press, New York, pp. 179–184.

    Google Scholar 

  164. Mogilnicka, E., Arbilla, S., Depoortere, H., and Langer, S. Z., 1980, Eur. J. Pharmacol. 65:289–292.

    PubMed  CAS  Google Scholar 

  165. Langer, S. Z., Zarifian, E., Briley, M., Raisman, R., and Sechter, D., 1981, Life Sci. 29:211–220.

    PubMed  CAS  Google Scholar 

  166. Briley, M. S., Langer, S. Z., Raisman, R., Sechter, D., and Zarifian, E., 1980, Science 209:303–305.

    PubMed  CAS  Google Scholar 

  167. Paul, S. M., Rehavi, M., Skolnick, P., Ballenger, J. C., and Goodwin, F. K., 1981, Arch. Gen. Psychiatry 38:1315–1317.

    PubMed  CAS  Google Scholar 

  168. Stanley, M., Virgilio, J., and Gershon, S., 1982, Science 216:1337–1339.

    PubMed  CAS  Google Scholar 

  169. Tuomoisto, J., Tukiainen, E., and Ahlfors, U. G., 1979, Psychopharmacology 65:141–147.

    Google Scholar 

  170. Vargaftig, B. B., Coignet, J. L., deVos, C. J., Grijsen, H., and Bonta, I. L., 1971, Eur. J. Pharmacol. 16:336–346.

    PubMed  CAS  Google Scholar 

  171. Whitaker, P. M., and Cross, A. J., 1980, Biochem. Pharmacol. 29:2709–2715.

    PubMed  CAS  Google Scholar 

  172. Dumbrille-Ross, A., Tang, S. W., and Seeman, P., 1980, Eur. J. Pharmacol. 68:395–396.

    PubMed  CAS  Google Scholar 

  173. Brunello, N., Chuang, D. M., and Costa, E., 1982, Eur. J. Pharmacol. 78:383–384.

    PubMed  CAS  Google Scholar 

  174. Mohler, H., Okada, T., and Enna, S. J., 1978, Brain Res. 156:391–395.

    PubMed  CAS  Google Scholar 

  175. Braestrup, C., Nielsen, M., and Squires, F. R., 1979, Life Sci. 24:347–350.

    PubMed  CAS  Google Scholar 

  176. Massotti, M., Alleva, F. R., Balázs, T., and Guidotti, A., 1980, Neuropharmacology 19:951–956.

    PubMed  CAS  Google Scholar 

  177. Rehavi, M., Skolnick, P., Hulihan, B., and Paul, S. M., 1981, Eur. J. Pharmacol. 70:597–599.

    PubMed  CAS  Google Scholar 

  178. Langer, S. Z., Raisman, R., and Briley, M., 1981, Eur. J. Pharmacol. 72:423–424.

    PubMed  CAS  Google Scholar 

  179. Lee, C.-M., and Snyder, S. H., 1981, Proc. Natl. Acad. Sci. U.S.A. 78:5250–5254.

    PubMed  CAS  Google Scholar 

  180. Brunello, N., Barbaccia, M. L., Chuang, D. M., and Costa, E., 1982, Neuropharmacology 21:1145–1149.

    PubMed  CAS  Google Scholar 

  181. Chuang, D. M., Barbaccia, M. L., Brunello, N., and Kinnier, W. J., 1982, Dynamics of Neurotransmission (I. Hanin, ed.), Raven Press, New York (in press).

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Preclinical Pharmacology, National Institute of Mental Health, Saint Elizabeths Hospital, Washington, D. C., 20032, USA

    De-Maw Chuang & E. Costa

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  1. De-Maw Chuang
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  2. E. Costa
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  1. Center for Neurochemistry, Wards Island, New York, USA

    Abel Lajtha

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Chuang, DM., Costa, E. (1984). Recognition Sites for Antidepressant Drugs. In: Lajtha, A. (eds) Handbook of Neurochemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4568-8_11

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  • DOI: https://doi.org/10.1007/978-1-4684-4568-8_11

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