Evidence for an Adenosine Receptor in Human Tissues

Kurpis, Laureen; John, David; Fox, Irving H.

doi:10.1007/978-1-4684-4553-4_97

Laureen Kurpis^4,5,
David John^4,5 &
Irving H. Fox^4,5

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 165))

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Abstract

Adenosine is an intermediate of the pathway of purine nucleotide degradation. Many biological properties of adenosine have been identified: It is toxic to mammalian and bacterial cells, and its presence is associated with inhibition of the immune response, coronary vasodilation, delayed neurotransmission, sedation, inhibition or stimulation of hormone secretion and changes in the metabolism of a number of tissues.¹

Supported by USPHS grant AM19674 and 5 MO1 RR00042 and a grant from Michigan Heart Association and Warner/Lambert-Parke/Davis.

Dr. John is supported by an Arthritis Foundation Postdoctoral Fellowship.

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Authors and Affiliations

Departments of Internal Medicine, The Human Purine Research Center, Ann Arbor, Michigan, USA
Laureen Kurpis, David John & Irving H. Fox
Biological Chemistry, University Hospitals, Ann Arbor, Michigan, USA
Laureen Kurpis, David John & Irving H. Fox

Authors

Laureen Kurpis
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David John
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Irving H. Fox
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Editor information

Editors and Affiliations

University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands
Chris H. M. M. De Bruyn
Guy’s Hospital Medical School, London, UK
H. Anne Simmonds
University of Vienna, Vienna, Austria
Mathias M. Müller

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Kurpis, L., John, D., Fox, I.H. (1984). Evidence for an Adenosine Receptor in Human Tissues. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4553-4_97

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DOI: https://doi.org/10.1007/978-1-4684-4553-4_97
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-4555-8
Online ISBN: 978-1-4684-4553-4
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