Abstract
In recent years it became apparent that fructose metabolism in the liver tissue has considerable effects on purine nucleotide metabolism. There is ample evidence that fructose metabolism is associated with acceleration of nucleotide degradation (1–5) and evidence is accumulating (6–8), indicating an acceleration effect of fructose also on purine synthesis.
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References
Perheentupa, J. and Raivio, K. (1967) Lancet 2, 528–531.
Fox, I.H. and Kelley, W.N. (1972) Metabolism 21, 713–721.
Simkin, P.A. (1972) Metabolism 21, 1029–1036.
Smith, C., Rovamo, L. and Raivio, K. (1977) Adv. Exp. Med. Biol. 76A, 535–541.
Van Den Berghe, G., Bronfman, M., Vanneste, R. and Hers H.G. (1977) Biochem. J. 162, 601–609.
Emmerson, B.T. (1974) Ann. Rheum. Dis. 33, 276,-280.
Raivio, K.O., Becker, M.A., Meyer, L.J., Greene, M.L., Muki, G. and Seegmiller, J.E. (1977) Metabolism 24, 861–869.
Itakura, M., Sabina, R.L., Heald, P.W. and Holmes, E.W. (1981) J. Clin. Invest. 67, 994–1002.
Seglen, P.O. (1976) Methods Cell Biol. 13, 29–83.
Zoref, E., De Vries, A. and Sperling, 0. (1975) J. Clin. Invest. 56, 1093–1099.
Johnson, W.Y., Stravic, B. and Chartrand, A. (1969) Proc. Soc. Exp. Med. Biol. 131, 8–12.
Fox, I.H. and Kelley, W.N. (1971) J. Biol. Chem. 246, 5739–5748.
Lowry, 0.H. and Lopez, J.A. (1946) J. Biol. Chem. 162, 421–428.
Zoref, E., Sivan, 0. and Sperling, 0. (1978) Bíochim. Biophys. Acta 521, 452–458.
Hershko, A., Razin, A. and Mager, J. (1969) Biochim. Biophys. Acta 184, 64–76.
Fox, I.H. and Kelley, W.N. (1972) J. Biol. Chem. 247, 2126–2131.
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© 1984 Plenum Press, New York
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Brosh, S., Boer, P., Sperling, O. (1984). Effects of Fructose on Purine Nucleotide Metabolism in Isolated Rat Hepatocytes. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4553-4_94
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DOI: https://doi.org/10.1007/978-1-4684-4553-4_94
Publisher Name: Springer, Boston, MA
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