Abstract
Glucagon increases DNA synthesis in regenerating rat liverl or even in nonoperated rat liver2 and an elevated level of plasma glucagon has been documented after hepatectomy.3 Other investigations have demonstrated that the concentration of 5-phosphoribosyl l-pyrophosphate(PP-ribose-P), which is an important regulator of purine biosynthesis de novo, and the rate of purine biosynthesis de novo itself are increased by glucagon administered in mice4 and in isolated rat hepatocytes.5,6
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References
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© 1984 Plenum Press, New York
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Itakura, M., Yamashita, K. (1984). The Chronologically Synchronous Elevation of Phosphoribosyl — Pyrophosphate and Cyclic AMP in Regenerating Rat Liver. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4553-4_89
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DOI: https://doi.org/10.1007/978-1-4684-4553-4_89
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