Skip to main content
SpringerLink
Log in

Evidence of Abnormal Renal Handling of Uric Acid in Patients with Nephrolithiasis and Hyperuricosuria

  • Chapter
Purine Metabolism in Man-IV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 165))

Abstract

A group of patients forming calcium oxalate stones are hyperuricosuric and it is thought that their excessive urate excretion contributes to calcium-stones formation1. The pathomechanisms invoked are dietary purine excess and endogenous uric acid overproduction, being defective tubular reabsorption of urate “unattractive” because uricemia was found to be normal in patients with recurrent calcium nephrolithiasis (RCN) and hyperuricosuria. Current studies were undertaken to define the incidence, role of diet, abnormalities of the renal handling of urate, and associated metabolic disturbances in patients with RCN and hyperuricosuria.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. F. L. Coe, Nephrolithiasis: pathogenesis and treatment. Year book of Medicine. Year book Publishers Inc. Chigago, London. (1978).

    Google Scholar 

  2. C. Y. C. Pak, F. Briton, R. Peterson, P. P. Ward, C. Northcurtt, M. A. Breslau, J. McQuire, K. Sakhace, S. Bush, M. Nicar, D. Norman, and P. Peters, Valoración ambulatoria de la nefrolitiasis: Clasificación, formas de presentación clinica y criterios diagnósticos, Am. J. Med. (spanish edition) 12: 11 (1980).

    Google Scholar 

  3. A. de Vries, and O. Sperling, Inborn hypouricemia due to isolated renal tubular defect, Biomedicine, 30: 75 (1979).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Internal Medicine and Clinical Biopathology, Ciudad Sanitaria La Paz, U. Autónoma, Madrid, Spain

    F. Mateos, J. G. Puig, E. Ma. Martínez, G. Gaspar, E. Herrero & J. A. Martínez Piñeiro

Authors
  1. F. Mateos
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. G. Puig
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Ma. Martínez
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Gaspar
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. E. Herrero
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. A. Martínez Piñeiro
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands

    Chris H. M. M. De Bruyn

  2. Guy’s Hospital Medical School, London, UK

    H. Anne Simmonds

  3. University of Vienna, Vienna, Austria

    Mathias M. Müller

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Plenum Press, New York

About this chapter

Cite this chapter

Mateos, F., Puig, J.G., Martínez, E.M., Gaspar, G., Herrero, E., Piñeiro, J.A.M. (1984). Evidence of Abnormal Renal Handling of Uric Acid in Patients with Nephrolithiasis and Hyperuricosuria. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4553-4_38

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-4553-4_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4555-8

  • Online ISBN: 978-1-4684-4553-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation