Abstract
Many Polynesian peoples exhibit a susceptibility to hyperuricaemia and gout.1,2 This predisposition is a feature of widely distributed populations and suggests a common genetic role.3 The mechanism has not been clearly established. Maori men are reported to have a prevalence of gout in excess of 10%. They are also prone to obesity, diabetes, and hypertension.3 It is not known whether renal dysfunction is an additional feature of this disease spectrum. The present study examined the current prevalence of hyperuricaemia and gout in a male Maori population of working age. An attempt was made to reassess the relationship of obesity and hypertension with hyperuricaemia; and to determine the prevalence of renal impairment. The renal excretion of uric acid was also estimated.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
I.A. Prior. Metabolic maladies in New Zealand Maoris. Brit. Med. J. 1: 1065 (1964)
P.Z. Zimmet S. Whitehouse, L. Jackson, K. Thoma. High prevalence of hyperuricaemia and gout in an urbanised Micronesian population. Brit. Med. J. 1: 1237 (1978)
I.A. Prior, B.S. Rose, H.P. Harvey, F. Davidson. Hyperuricaemia, gout and diabetic abnormality in Polynesian people. Lancet 1: 333 (1966)
T. Gibson, J. Highton, C. Potter, H.A. Simonds. Renal impairment and gout. Ann. Rheum. Dis. 39: 417 (1980)
J.M. Stanhope and I.A. Prior. Uric acid, joint morbidity and streptococcal antibodies in Maori and European teenagers. Ann. Rheum. Dis. 34: 359 (1975)
W.M. Mikkelsen, H.J. Dodge, I.F. Duff, I.H. Kato. Estimates of the prevalence of rheumatic disease in the population of Tecumseh, Michigan. J. Chron. Dis. 20: 351 (1967)
J. Zalokar, J. Lellouch, J.R. Claude. Goutte et uricémie dans une population de 4663 hommes jeunes actifs. Sem. Hop. Paris 57: 664 (1981)
G.W. Brauer and I.A. Prior. A prospective study of gout in New Zealand Maoris. Ann. Rheum. Dis. 37: 466 (1978)
B.W. Christmas and A.S. Turner. Prevalence of high blood pressure treated and untreated in an urban adult New Zealand population: Napier 1973. New Zealand Med. J. 86: 419 (1977)
T.H. Steele and R.E. Rieselbach. The renal mechanism for urate homeostasis in man. Am. J. Med. 43: 868 (1967)
M.L. Snaith and J.T. Scott. Uric acid clearance in patients with gout and normal subjects. Ann. Rheum. Dis. 30: 285 (1971)
M.A. Ogryzlo, M.B. Urowitz, H.M. Weber, J.B. Houpt. Effects of allopurinol on gouty and non-gouty uric acid nephropathy. Ann. Rheum. Dis. 25: 673 (1966)
C.A. Nugent and F.H. Tyler. The renal excretion of uric acid in patients with gout and in non-gouty subjects. J. Clin. Invest. 38: 1890 (1959)
L.A. Healey and P.S. Bayani-Sioson. A defect in the renal excretion of uric acid in Filipinos. Arthritis Rheum. 14: 721 (1971)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Plenum Press, New York
About this chapter
Cite this chapter
Gibson, T., Waterworth, R., Hatfield, P., Robinson, G., Bremner, K. (1984). Hyperuricaemia in Young New Zealand Maori Men. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4553-4_22
Download citation
DOI: https://doi.org/10.1007/978-1-4684-4553-4_22
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-4555-8
Online ISBN: 978-1-4684-4553-4
eBook Packages: Springer Book Archive