Abstract
Experimental procedures for determining diffusion coefficients of compact macromolecules within biological gels and partition coefficients between gels and surrounding solutions are described. Results are presented for dextran fractions diffusing within calcium alginate and agarose gels. A gel concentration — hydrodynamic diameter superposition principle is shown to apply, and a method for calculating the molecular weight per unit length of the fibrous gel structure from the results is discussed, together with the significance of the measured partition coefficients.
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© 1983 Plenum Press, New York
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Sellen, D.B. (1983). The Diffusion of Compact Macromolecules Through Biological Gels. In: Earnshaw, J.C., Steer, M.W. (eds) The Application of Laser Light Scattering to the Study of Biological Motion. NATO Advanced Science Institutes Series, vol 59. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4487-2_12
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DOI: https://doi.org/10.1007/978-1-4684-4487-2_12
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