Abstract
Since the identification in 1909 of Trypanosoma cruzi as the causative agent of Chagas’ disease, a large body of literature has arisen relating to the nature of the disease. Two observations in particular initially stimulated my interest in the immunology of Chagas’ disease. The first was that the severity of the disease that occurs following the initial infection with T. cruzi (called the acute stage of the disease) can range from asymptomatic to lethal (1). This variation in what can be termed natural resistance may be the result of multiple genetic and environmental factors, but it is easy to imagine how differences in the immune responses made by individuals could be critical for influencing the ensuing course of the disease.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Segovia, S.A., et al. (1974). Bull. WHO, 50:459.
Teixeira, A.R.L. (1977). In “Immunity to Blood Parasites of-Animals and Man” (L. Miller, J. Pino, and J. McKelvey, eds.), p. 243. Plenum, New York.
Pizzi, T., Agosin, M., Christen, R., Hoecker, G., and Neghme, A. (1949). Boletin Informaciones Parasitarias Chilenas, 4:48.
Seah, S., and Marsden, P.D. (1969). Ann Trop. Med. Parasitol., 63:211.
Hauschka, T.S., Goodwin, M.B., Palmquist, J. and Brown, E. (1950). Am. J. Trop. Med., 30:1.
Trischmann, T., Tanowitz, H., Wittner, M. and Bloom, B. (1978). Exp. Parasitol., 45:160.
Hanson, W.L., and Roberson, E.L. (1974). J. Protozool., 21:512.
Hanson, W.L. (1977). In “Chagas’ Disease”. Pan American Health Organization.Scientific publication No. 347, p. 22.
Hauschka, T.S. (1947). J. Parasitol. 33:399.
Culbertson, J.T., and Kessler, W.R. (1942). J. Parasitol., 28:155.
Blackwell, J., Freeman, J., and Bradley, D. (1980). Nature, 283:72.
Williams, D.M., Grumet, F.C., and Remington, J. S. (1978). Infect. Immun., 19:416.
Taylor, B.A., Bailey, D.W., Cherry, M., Riblet, R., and Weigert, M. (1975). Nature, 256:644.
Howard, J.G., Hale, C., and Liew, F.Y. (1980), Nature, 288:161.
Hormaeche, C.E. (1979). Immunology, 37:319.
Budzko, D.B., Pizzimenti, M.C., and Kierszenbaum, F. (1975). Infect. Immun., 11:86.
Lopez, A.F., Bunn Moreno, M.M., and Sanderson, C.J. (1978). Int. J. Parasitol., 8:485.
Hoff, R. (1975). J. Exp. Med., 142:299.
Kuhn, R.E., and Murnane, J.E. (1977). Exp. Parasitol., 41:66.
Trischmann, T.M., and Bloom, B.R. (1980). Exp. Parasitol., 49:225.
Brener, Z. (1980). Adv. Parasitol., 18:247.
Kierszenbaum, F. (1980). J. Parasitol. 66:673.
Gordon, J. (1979). J. Immunol. Meth. 25:277.
McHardy, N. (1978). Trans. R. Soc. Trop. Med, Hyg., 72:201.
Ribeiro Dos Santos, R., and Hudson, L. (1980). Parasite Immunol., 2:1.
Abrahamsohn, I.A., and Kloetzel, J.K. (1980), Parasitology, 80:147.
Nogueira, N., Chaplan, S. and Cohn, Z. (1980). J. Exp. Med., 152:447.
Santos-Buch, C.A., and Teixeira, A.R.L. (1974), J. Exp. Med., 140:38.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Plenum Press, New York
About this paper
Cite this paper
Trischmann, T.M. (1983). Natural and Acquired Resistance to Trypanosoma Cruzi . In: Eisenstein, T.K., Actor, P., Friedman, H. (eds) Host Defenses to Intracellular Pathogens. Advances in Experimental Medicine and Biology, vol 162. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4481-0_35
Download citation
DOI: https://doi.org/10.1007/978-1-4684-4481-0_35
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-4483-4
Online ISBN: 978-1-4684-4481-0
eBook Packages: Springer Book Archive