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Role of Natural Killer Cells and of Interferon in Natural Resistance against Virus Infections

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Macrophages and Natural Killer Cells

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 155))

Abstract

There are a number of experimental findings that are fairly well established:

  1. (a)

    Interferons cause an antiviral effect in tissue culture (1).

  2. (b)

    Injection of interferon causes antiviral protection in vivo (for a review see Ref. 2).

  3. (c)

    Injection of a variety of viruses causes rapid interferon production in vivo, both at the infection site (for example in the peritoneal cavity) and in the serum (3).

  4. (d)

    Injection of interferon or interferon inducers (including viruses) causes activation of Natural Killer (NK) cells in vivo (4).

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Author information

Authors and Affiliations

  1. Institute of Virus Research, German Cancer Research Center, Heidelberg, Germany

    H. Kirchner, H. Engler, R. Zawatzky & L. Schindler

Authors
  1. H. Kirchner
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  2. H. Engler
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  3. R. Zawatzky
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  4. L. Schindler
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Editor information

Editors and Affiliations

  1. College of Medicine, University of Florida, Gainesville, Florida, USA

    Sigurd J. Normann

  2. Department of Medicine, Swiss Research Institute, Davos, Switzerland

    Ernst Sorkin

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© 1982 Plenum Press, New York

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Kirchner, H., Engler, H., Zawatzky, R., Schindler, L. (1982). Role of Natural Killer Cells and of Interferon in Natural Resistance against Virus Infections. In: Normann, S.J., Sorkin, E. (eds) Macrophages and Natural Killer Cells. Advances in Experimental Medicine and Biology, vol 155. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4394-3_86

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  • DOI: https://doi.org/10.1007/978-1-4684-4394-3_86

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4396-7

  • Online ISBN: 978-1-4684-4394-3

  • eBook Packages: Springer Book Archive

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