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Identification of a T Cell Hybridoma which Produces Extraordinary Quantities of Macrophage Activating Factor

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Macrophages and Natural Killer Cells

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 155))

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Abstract

It is now generally accepted that under certain conditions the macrophage can express effector cell function toward a variety of neoplastic cells (1,2). Current evidence indicates that the macrophage tumoricidal response is initiated and/or augmented by a T cell product, denoted as macrophage activating factor or MAF (3–7). MAF is thought to alter or “prime” the macrophage in such a way as to make it responsive to a second or “triggering” signal which ultimately activates the tumoricidal potential of the cell (8–12).

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© 1982 Plenum Press, New York

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Schreiber, R.D., Altman, A., Katz, D.H. (1982). Identification of a T Cell Hybridoma which Produces Extraordinary Quantities of Macrophage Activating Factor. In: Normann, S.J., Sorkin, E. (eds) Macrophages and Natural Killer Cells. Advances in Experimental Medicine and Biology, vol 155. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4394-3_52

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  • DOI: https://doi.org/10.1007/978-1-4684-4394-3_52

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4396-7

  • Online ISBN: 978-1-4684-4394-3

  • eBook Packages: Springer Book Archive

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