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Macrophages and Natural Killer Cells pp 189–193Cite as

Properties of the Factor Increasing Monocytopoiesis (FIM) in Rabbit Peripheral Blood

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 155))

Abstract

Monocyte production in mice is stimulated during the initial phase of acute inflammation by a humoral factor called the factor increasing monocytopoiesis (FIM) (1). This factor, a protein of about 20,000 daltons without detectable carbohydrates at its active site, induces monocytosis by stimulating proliferation of promonocytes in the bone marrow (2). The number of granulocytes and lymphocytes is not affected.

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References

  1. Waarde, D. van, Hulsing-Hesselink, E., Sandkuyl, L. A., and Furth, R. van, Blood 50:141, 1977.

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  2. Waarde, D. van, Hulsing-Hesselink, E., and Furth, R. van, Blood 50:727, 1977.

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  3. Waarde, D. van, Bakker, S., Vliet, J. van, Angulo, A. F., and Furth, R. van, J. Reticuloendothelial Soc. 24:197, 1978.

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  4. Sluiter, W., Waarde, D. van, Hulsing-Hesselink, E., Elzenga-Claasen, I., and Furth, R. van, in “Mononuclear Phagocytes-Functional Aspects” (R. van Furth, ed.), p. 325, Martinus Nijhoff Publishers, The Hague, Boston, London, 1980.

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  5. Sluiter, W., Elzenga-Claasen, I., Hulsing-Hesselink, E., and Furth, R. van, submitted for publication.

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  6. Worton, R. G., McCullock, E. A., Till, J. E., J. Cell. Physiol. 74:171, 1969.

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Author information

Authors and Affiliations

  1. Department of Infectious Diseases, University Hospital, Leiden, The Netherlands

    W. Sluiter, I. Elzenga-Claasen, E. Hulsing-Hesselink & R. van Furth

Authors
  1. W. Sluiter
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  2. I. Elzenga-Claasen
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  3. E. Hulsing-Hesselink
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  4. R. van Furth
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Editor information

Editors and Affiliations

  1. College of Medicine, University of Florida, Gainesville, Florida, USA

    Sigurd J. Normann

  2. Department of Medicine, Swiss Research Institute, Davos, Switzerland

    Ernst Sorkin

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© 1982 Plenum Press, New York

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Sluiter, W., Elzenga-Claasen, I., Hulsing-Hesselink, E., van Furth, R. (1982). Properties of the Factor Increasing Monocytopoiesis (FIM) in Rabbit Peripheral Blood. In: Normann, S.J., Sorkin, E. (eds) Macrophages and Natural Killer Cells. Advances in Experimental Medicine and Biology, vol 155. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4394-3_17

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  • DOI: https://doi.org/10.1007/978-1-4684-4394-3_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4396-7

  • Online ISBN: 978-1-4684-4394-3

  • eBook Packages: Springer Book Archive

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