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An in Vivo Aggregometer

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Part of the book series: NATO Advanced Science Institutes Series ((NSSA,volume 54))

Abstract

The method of aggregometry introduced by Born [1] in 1962 has been used extensively to study platelet aggregation and disaggregation in vitro and ex vivo. Although it is generally accepted that in vitro data does not always reflect in vivo data [2], fewer studies have been undertaken on platelets in vivo. Such, in vivo studies are limited by the cumbersome and invasive nature of existing techniques [3] which has prompted development of a simple, minimally invasive technique for the continuous monitoring of radiolabeled platelets in vivo [4].

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References

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© 1983 Plenum Press, New York

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Page, C.P., Paul, W. (1983). An in Vivo Aggregometer. In: Berti, F., Folco, G., Velo, G.P. (eds) Leukotrienes and Prostacyclin. NATO Advanced Science Institutes Series, vol 54. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4391-2_14

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  • DOI: https://doi.org/10.1007/978-1-4684-4391-2_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4393-6

  • Online ISBN: 978-1-4684-4391-2

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