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The Role of Humoral Factors in Endotoxin-Induced Reactions

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Book cover Beneficial Effects of Endotoxins

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Abstract

Within the last half-decade it has become abundantly clear that many of the biological effects of bacterial endotoxin are mediated by what is believed to be a number of different protein and glycoprotein molecules (Berry, 1977; Moore and Berry, 1982). These molecules are derived from cells of the reticuloendothelial system (RES), especially macrophages but from other cells as well. It is intriguing to realize that a diffuse tissue such as the RES qualifies functionally as part of the endocrine system and the mediators as hormones. There is no anatomical or physiological reason why this should not be true since chromaffin tissue, a source of epinephrine and norephinephrine, is also diffusely distributed.

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Authors and Affiliations

  1. Department of Microbiology, University of Texas, Austin, Texas, 78712, USA

    L. Joe Berry & Jeanne E. Gaska

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  1. L. Joe Berry
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  2. Jeanne E. Gaska
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  1. Center for Oral Health Research, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Alois Nowotny

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© 1983 Plenum Press, New York

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Berry, L.J., Gaska, J.E. (1983). The Role of Humoral Factors in Endotoxin-Induced Reactions. In: Nowotny, A. (eds) Beneficial Effects of Endotoxins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4364-6_18

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  • DOI: https://doi.org/10.1007/978-1-4684-4364-6_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4366-0

  • Online ISBN: 978-1-4684-4364-6

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