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Genetic Toxicology pp 403–424Cite as

Mutation In Vivo in Human Somatic Cells: Studies Using Peripheral Blood Mononuclear Cells

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Part of the book series: Basic Life Sciences ((BLSC,volume 6))

Abstract

We review here our efforts to develop a direct mutagenicity test system for detecting somatic cell mutations occurring in vivo in man. Our specific goal is to provide a useful test for directly quantifying mutant cells in human blood samples.

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Author information

Authors and Affiliations

  1. Department of Medicine and Medical Microbiology, University of Vermont, Burlington, Vermont, 05405, USA

    Richard J. Albertini M.D., PhD., David L. Sylwester, Bruce D. Dannenberg & Elizabeth F. Allen

  2. Department of Medicine, University of Vermont College of Medicine, Given Building E305, Burlington, Vermont, 05405, USA

    Richard J. Albertini M.D., PhD.

Authors
  1. Richard J. Albertini M.D., PhD.
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  2. David L. Sylwester
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  3. Bruce D. Dannenberg
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  4. Elizabeth F. Allen
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Editor information

Editors and Affiliations

  1. University of California, Davis, Davis, California, USA

    Raymond A. Fleck

  2. Associated Universities, Inc., Washington, D.C., USA

    Alexander Hollaender

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© 1982 Plenum Press, New York

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Albertini, R.J., Sylwester, D.L., Dannenberg, B.D., Allen, E.F. (1982). Mutation In Vivo in Human Somatic Cells: Studies Using Peripheral Blood Mononuclear Cells. In: Fleck, R.A., Hollaender, A. (eds) Genetic Toxicology. Basic Life Sciences, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4352-3_29

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  • DOI: https://doi.org/10.1007/978-1-4684-4352-3_29

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4354-7

  • Online ISBN: 978-1-4684-4352-3

  • eBook Packages: Springer Book Archive

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